UGT1A6
UDP-glucuronosyltransferase 1-6
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.88 | ||
chemical | 0.88 | ||
trait | 0.86 | ||
molecular function | 0.79 | ||
disease | 0.78 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Biological oxidations | ||||
Reactome | Glucuronidation | ||||
Reactome | Metabolism | ||||
Reactome | Phase II - Conjugation of compounds | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Biological oxidations | ||||
Glucuronidation | ||||
Metabolism | ||||
Phase II - Conjugation of compounds | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
bilirubin measurement | 16 | 74 | 136 | 100 | |||||
vitamin D measurement | 4 | 5 | 5 | 96.7 | |||||
blood metabolite measurement | 1 | 2 | 8 | 95.6 | |||||
testosterone measurement | 7 | 4 | 7 | 92.6 | |||||
serum metabolite measurement | 2 | 2 | 10 | 92.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
bilirubin measurement | 136 | 100 | |||||
vitamin D measurement | 5 | 96.7 | |||||
blood metabolite measurement | 8 | 95.6 | |||||
testosterone measurement | 7 | 92.6 | |||||
serum metabolite measurement | 10 | 92.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:3580629 | 394435 | ||||||
Dog | UDP glucuronosyltransferase 1 family, polypeptide A6 | 403629 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
Dog | UDP glucuronosyltransferase 1 family, polypeptide A6 | |||||
PMID | Year | Title |
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