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Tbio
UBXN2A
UBX domain-containing protein 2A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000309033
  • ENSP00000312107
  • ENSG00000173960
  • ENST00000404924
  • ENSP00000385525

Symbol
  • UBXD4
  • UBXD4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.9
virus perturbation
0.79
transcription factor binding site profile
0.72
small molecule perturbation
0.63
disease perturbation
0.56


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.36   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 89   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.36   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 89   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 11
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (47)
VCP
Tchem
Family:  Enzyme
Novelty:  0.00103317
p_int:  0.999999998
p_ni:  2e-9
Score:  0.938
Data Source:  BioPlex,STRINGDB
PPP1R11
Tbio
Family:  Enzyme
Novelty:  0.08166535
p_int:  0.999987517
p_ni:  0.000012221
p_wrong:  2.62e-7
Score:  0.586
Data Source:  BioPlex,STRINGDB
ASPSCR1
Tbio
Novelty:  0.01172319
p_int:  0.999981744
p_ni:  0.000018256
Score:  0.94
Data Source:  BioPlex,STRINGDB
UBXN6
Tbio
Novelty:  0.08383376
p_int:  0.99982359
p_ni:  1.43e-7
p_wrong:  0.000176267
Score:  0.951
Data Source:  BioPlex,STRINGDB
PPP1R7
Tbio
Family:  Enzyme
Novelty:  0.02088568
p_int:  0.963412572
p_ni:  0.036587428
Score:  0.409
Data Source:  BioPlex,STRINGDB
UBXN10
Tdark
Novelty:  1.06788836
Score:  0.853
Data Source:  STRINGDB
UBXN7
Tbio
Novelty:  0.07437638
Score:  0.842
Data Source:  STRINGDB
HSPA9
Tchem
Novelty:  0.00235171
Score:  0.796
Data Source:  STRINGDB
UBXN11
Tbio
Novelty:  0.03165477
Score:  0.794
Data Source:  STRINGDB
NPLOC4
Tbio
Novelty:  0.01690434
Score:  0.739
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (33)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte measurement
3
6
10
98.8
lymphocyte count
3
4
4
98.3
reticulocyte count
7
6
16
98.2
appendicular lean mass
3
4
7
97.2
mean corpuscular volume
1
3
3
94.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte measurement
10
98.8
lymphocyte count
4
98.3
reticulocyte count
16
98.2
appendicular lean mass
7
97.2
mean corpuscular volume
3
94.9
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
UBX domain protein 2A
VGNC:404
470326
Macaque
UBX domain protein 2A
718340
Mouse
MGI:2442310
217379
Rat
RGD:1589027
685859
Dog
UBX domain protein 2A
VGNC:48098
482992
Species
Name
OMA
EggNOG
Inparanoid
Chimp
UBX domain protein 2A
Macaque
UBX domain protein 2A
Mouse
Rat
Dog
UBX domain protein 2A
Publication Statistics
PubMed Score 4.36
PubMed score by year
PubTator Score 2.42
PubTator score by year
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Related Publications
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PMID
Year
Title