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Tdark
UBXN10
UBX domain-containing protein 10

Protein Summary
Description
VCP/p97-binding protein required for ciliogenesis (PubMed:26389662). Acts as a tethering factor that facilitates recruitment of VCP/p97 to the intraflagellar transport complex B (IFT-B) in cilia (PubMed:26389662). UBX domain-containing proteins act as tethering factors for VCP/p97 and may specify substrate specificity of VCP/p97 (PubMed:26389662).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000375099
  • ENSP00000364240
  • ENSG00000162543

Symbol
  • UBXD3
  • UBXD3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.73
transcription factor
0.64
microRNA
0.61
histone modification site profile
0.46
tissue
0.42


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.21   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 157   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.21   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 157   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (38)
UBXN2A
Tbio
Novelty:  0.52282698
Score:  0.853
Data Source:  STRINGDB
OR10G6
Tdark
Family:  oGPCR
Novelty:  11.18644068
Score:  0.801
Data Source:  STRINGDB
UBXN8
Tbio
Novelty:  0.12560109
Score:  0.754
Data Source:  STRINGDB
UBXN6
Tbio
Novelty:  0.08383376
Score:  0.731
Data Source:  STRINGDB
VCP
Tchem
Family:  Enzyme
Novelty:  0.00103317
Score:  0.725
Data Source:  STRINGDB
NSFL1C
Tbio
Novelty:  0.05494848
Score:  0.725
Data Source:  STRINGDB
CLUAP1
Tbio
Novelty:  0.08002286
Score:  0.691
Data Source:  STRINGDB
UFD1
Tbio
Novelty:  0.01230296
Score:  0.69
Data Source:  STRINGDB
NPLOC4
Tbio
Novelty:  0.01690434
Score:  0.683
Data Source:  STRINGDB
UBXN7
Tbio
Novelty:  0.07437638
Score:  0.672
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
1
2
2
51.2
telomere length
1
1
1
10.3
polyunsaturated fatty acid measurement
1
1
1
10.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
2
51.2
telomere length
1
10.3
polyunsaturated fatty acid measurement
1
10.3
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2443123
212190
Rat
RGD:1308335
298577
Dog
UBX domain protein 10
VGNC:48096
487395
Horse
UBX domain protein 10
VGNC:24753
100058492
Cow
UBX domain protein 10
VGNC:36623
538586
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
UBX domain protein 10
Horse
UBX domain protein 10
Cow
UBX domain protein 10
Publication Statistics
PubMed Score 1.21
PubMed score by year
PubTator Score 0.90
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title