UBTF
Nucleolar transcription factor 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 1 | ||
transcription factor perturbation | 0.98 | ||
disease perturbation | 0.93 | ||
protein complex | 0.89 | ||
hub protein | 0.88 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Epigenetic regulation of gene expression | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | Negative epigenetic regulation of rRNA expression | ||||
Reactome | NoRC negatively regulates rRNA expression | ||||
Reactome | RNA Polymerase I Promoter Clearance | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Epigenetic regulation of gene expression | ||||
Gene expression (Transcription) | ||||
Negative epigenetic regulation of rRNA expression | ||||
NoRC negatively regulates rRNA expression | ||||
RNA Polymerase I Promoter Clearance | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | CAFA | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Sequence Model (ISM) | NTNU_SB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
reticulocyte count | 6 | 6 | 9 | 98.8 | |||||
mean corpuscular volume | 2 | 4 | 4 | 98.1 | |||||
reticulocyte measurement | 3 | 4 | 6 | 97.8 | |||||
mean reticulocyte volume | 1 | 4 | 4 | 96.5 | |||||
red blood cell distribution width | 4 | 2 | 4 | 92.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
reticulocyte count | 9 | 98.8 | |||||
mean corpuscular volume | 4 | 98.1 | |||||
reticulocyte measurement | 6 | 97.8 | |||||
mean reticulocyte volume | 4 | 96.5 | |||||
red blood cell distribution width | 4 | 92.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | upstream binding transcription factor, RNA polymerase I | 454726 | ||||||
Macaque | upstream binding transcription factor, RNA polymerase I | 711597 | ||||||
Mouse | MGI:98512 | 21429 | ||||||
Rat | RGD:3927 | 25574 | ||||||
Dog | upstream binding transcription factor, RNA polymerase I | 480503 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | upstream binding transcription factor, RNA polymerase I | |||||
Macaque | upstream binding transcription factor, RNA polymerase I | |||||
Mouse | ||||||
Rat | ||||||
Dog | upstream binding transcription factor, RNA polymerase I | |||||
PMID | Year | Title |
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