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Tbio
UBN2
Ubinuclein-2

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.36   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 81   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.36   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 81   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (70)
ASF1B
Tbio
Novelty:  0.05716701
p_int:  0.999999983
p_ni:  1.7e-8
p_wrong:  1e-9
Score:  0.266
Data Source:  BioPlex,STRINGDB
ASF1A
Tchem
Novelty:  0.02544466
p_int:  0.999999982
p_ni:  1.7e-8
p_wrong:  1e-9
Score:  0.578
Data Source:  BioPlex,STRINGDB
CDX1
Tbio
Family:  TF
Novelty:  0.00815821
p_int:  0.999858599
p_ni:  0.000141399
p_wrong:  2e-9
Data Source:  BioPlex
HMGA1
Tbio
Family:  TF
Novelty:  0.00185669
p_int:  0.999590408
p_ni:  0.000409592
Data Source:  BioPlex
LANCL1
Tbio
Novelty:  0.06479031
p_int:  0.999422624
p_ni:  0.000577374
p_wrong:  1e-9
Score:  0.523
Data Source:  BioPlex,STRINGDB
TFAP4
Tbio
Family:  TF
Novelty:  0.03155887
p_int:  0.99938627
p_ni:  0.000613378
p_wrong:  3.52e-7
Score:  0.195
Data Source:  BioPlex,STRINGDB
TEAD2
Tbio
Family:  TF
Novelty:  0.02487024
p_int:  0.991286065
p_ni:  0.008707913
p_wrong:  0.000006022
Score:  0.187
Data Source:  BioPlex,STRINGDB
ALX3
Tbio
Family:  TF
Novelty:  0.02711914
p_int:  0.9633365
p_ni:  0.014387538
p_wrong:  0.022275962
Score:  0.167
Data Source:  BioPlex,STRINGDB
MEF2B
Tbio
Family:  TF
Novelty:  0.03094093
p_int:  0.947954582
p_ni:  0.020858544
p_wrong:  0.031186874
Data Source:  BioPlex
H3F3A
Tbio
Novelty:  0.00508186
Score:  0.758
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
left ventricular diastolic function measurement
1
1
0
1.7
21.5
high density lipoprotein cholesterol measurement
1
1
1
17.8
comparative body size at age 10, self-reported
1
1
1
17.8
body mass index
1
1
1
17.4
body height
1
1
1
11.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
left ventricular diastolic function measurement
0
1.7
21.5
high density lipoprotein cholesterol measurement
1
17.8
comparative body size at age 10, self-reported
1
17.8
body mass index
1
17.4
body height
1
11.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ubinuclein 2
VGNC:4557
463770
Macaque
ubinuclein 2
711019
Mouse
MGI:2444236
320538
Rat
RGD:1310722
312248
Dog
ubinuclein 2
VGNC:48082
482776
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ubinuclein 2
Macaque
ubinuclein 2
Mouse
Rat
Dog
ubinuclein 2
Publication Statistics
PubMed Score 11.36
PubMed score by year
PubTator Score 1.20
PubTator score by year
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Related Publications
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PMID
Year
Title