Protein Summary
- ENST00000473989
- ENSP00000418648
- ENSG00000157741
- KIAA2030
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.81 | ||
kinase perturbation | 0.76 | ||
microRNA | 0.7 | ||
tissue | 0.64 | ||
transcription factor binding site profile | 0.6 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 11.36 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 81 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 11.36 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 81 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 0
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (70)
ASF1B
Novelty: 0.05716701
p_int: 0.999999983
p_ni: 1.7e-8
p_wrong: 1e-9
Score: 0.266
Data Source: BioPlex,STRINGDB
ASF1A
Novelty: 0.02544466
p_int: 0.999999982
p_ni: 1.7e-8
p_wrong: 1e-9
Score: 0.578
Data Source: BioPlex,STRINGDB
CDX1
Family: TF
Novelty: 0.00815821
p_int: 0.999858599
p_ni: 0.000141399
p_wrong: 2e-9
Data Source: BioPlex
LANCL1
Novelty: 0.06479031
p_int: 0.999422624
p_ni: 0.000577374
p_wrong: 1e-9
Score: 0.523
Data Source: BioPlex,STRINGDB
TFAP4
Family: TF
Novelty: 0.03155887
p_int: 0.99938627
p_ni: 0.000613378
p_wrong: 3.52e-7
Score: 0.195
Data Source: BioPlex,STRINGDB
TEAD2
Family: TF
Novelty: 0.02487024
p_int: 0.991286065
p_ni: 0.008707913
p_wrong: 0.000006022
Score: 0.187
Data Source: BioPlex,STRINGDB
ALX3
Family: TF
Novelty: 0.02711914
p_int: 0.9633365
p_ni: 0.014387538
p_wrong: 0.022275962
Score: 0.167
Data Source: BioPlex,STRINGDB
MEF2B
Family: TF
Novelty: 0.03094093
p_int: 0.947954582
p_ni: 0.020858544
p_wrong: 0.031186874
Data Source: BioPlex
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (2)
Components (2)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | HPA | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Disease Associations ()
GWAS Traits (5)
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
left ventricular diastolic function measurement | 1 | 1 | 0 | 1.7 | 21.5 | ||||
high density lipoprotein cholesterol measurement | 1 | 1 | 1 | 17.8 | |||||
comparative body size at age 10, self-reported | 1 | 1 | 1 | 17.8 | |||||
body mass index | 1 | 1 | 1 | 17.4 | |||||
body height | 1 | 1 | 1 | 11.5 | |||||
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
left ventricular diastolic function measurement | 0 | 1.7 | 21.5 | ||||
high density lipoprotein cholesterol measurement | 1 | 17.8 | |||||
comparative body size at age 10, self-reported | 1 | 17.8 | |||||
body mass index | 1 | 17.4 | |||||
body height | 1 | 11.5 | |||||
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ubinuclein 2 | VGNC:4557 | 463770 | |||||
Macaque | ubinuclein 2 | 711019 | ||||||
Mouse | MGI:2444236 | 320538 | ||||||
Rat | RGD:1310722 | 312248 | ||||||
Dog | ubinuclein 2 | VGNC:48082 | 482776 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ubinuclein 2 | |||||
Macaque | ubinuclein 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | ubinuclein 2 | |||||
Publication Statistics
PubMed Score 11.36
PubMed score by year
PubTator Score 1.20
PubTator score by year
Related Publications
Text Mined References (6)
Items per page:
0 of 0
PMID | Year | Title |
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