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Tdark
UAP1L1
UDP-N-acetylhexosamine pyrophosphorylase-like protein 1

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.25   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 80   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.25   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (67)
PGM3
Tbio
Family:  Enzyme
Novelty:  0.00515842
Score:  0.981
Data Source:  STRINGDB
PCBD1
Tbio
Family:  Enzyme
Novelty:  0.01564376
Score:  0.976
Data Source:  STRINGDB
AFMID
Tbio
Family:  Enzyme
Novelty:  0.02027656
Score:  0.976
Data Source:  STRINGDB
GNE
Tbio
Family:  Enzyme
Novelty:  0.00285751
Score:  0.933
Data Source:  STRINGDB
UAP1
Tbio
Family:  Enzyme
Novelty:  0.02034314
Score:  0.806
Data Source:  STRINGDB
GNPNAT1
Tbio
Family:  Enzyme
Novelty:  0.01739665
Score:  0.761
Data Source:  STRINGDB
SLC37A2
Tbio
Family:  Transporter
Novelty:  0.08172762
Score:  0.74
Data Source:  STRINGDB
SLC37A1
Tbio
Family:  Transporter
Novelty:  0.11329328
Score:  0.74
Data Source:  STRINGDB
SLC35D1
Tbio
Family:  Transporter
Novelty:  0.08762897
Score:  0.734
Data Source:  STRINGDB
RUFY4
Tbio
Novelty:  0.95990073
Score:  0.678
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
3
4
91.5
monocyte percentage of leukocytes
2
2
2
88
leukocyte count
2
2
3
70.2
lymphocyte percentage of leukocytes
1
1
1
49.5
platelet count
1
1
1
39.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
4
91.5
monocyte percentage of leukocytes
2
88
leukocyte count
3
70.2
lymphocyte percentage of leukocytes
1
49.5
platelet count
1
39.6
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VGNC:14399
464884
Mouse
MGI:2443318
227620
Rat
RGD:1310630
296560
Dog
UDP-N-acetylhexosamine pyrophosphorylase-like protein 1
491239
Horse
UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28082]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
Mouse
Rat
Dog
UDP-N-acetylhexosamine pyrophosphorylase-like protein 1
Horse
UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28082]
Publication Statistics
PubMed Score 4.25
PubMed score by year
PubTator Score 0.37
PubTator score by year
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Related Publications
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PMID
Year
Title