U2SURP
U2 snRNP-associated SURP motif-containing protein
Protein Summary
- ENST00000473835
- ENSP00000418563
- ENSG00000163714
- KIAA0332
- SR140
- SR140
- fSAPa
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
interacting protein | 1 | ||
transcription factor perturbation | 0.97 | ||
transcription factor binding site profile | 0.92 | ||
histone modification site profile | 0.86 | ||
co-expressed gene | 0.85 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 5.26 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 123 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 5.26 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 123 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (232)
RBM17
Novelty: 0.04840999
p_int: 0.999976791
p_ni: 0.000023209
Score: 0.985
Data Source: BioPlex,STRINGDB
PLOD1
Family: Enzyme
Novelty: 0.00905345
p_int: 0.997504079
p_ni: 0.002495921
Data Source: BioPlex
SNRPE
Novelty: 0.02033423
p_int: 0.992792453
p_ni: 0.007207547
Score: 0.934
Data Source: BioPlex,STRINGDB
PHF5A
Family: Epigenetic
Novelty: 0.02989472
p_int: 0.983286308
p_ni: 0.016713691
Score: 0.914
Data Source: BioPlex,STRINGDB
FGFR2
Family: Kinase
Novelty: 0.00066613
p_int: 0.982193566
p_ni: 0.017806434
Data Source: BioPlex
CSTF2T
Novelty: 0.11811814
p_int: 0.974643906
p_ni: 0.025356092
p_wrong: 2e-9
Score: 0.919
Data Source: BioPlex,STRINGDB
SFSWAP
Novelty: 0.2236256
p_int: 0.969198955
p_ni: 0.030801045
Score: 0.712
Data Source: BioPlex,STRINGDB
WDFY2
Novelty: 0.01835759
p_int: 0.964361869
p_ni: 0.035638131
Score: 0.324
Data Source: BioPlex,STRINGDB
ZRSR2
Novelty: 0.03449891
p_int: 0.939607217
p_ni: 0.060392783
Score: 0.638
Data Source: BioPlex,STRINGDB
SNRPB2
Novelty: 0.17219587
p_int: 0.930657098
p_ni: 0.069342902
Score: 0.919
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (5)
Reactome (4)
KEGG (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Metabolism of RNA | ||||
Reactome | Processing of Capped Intron-Containing Pre-mRNA | ||||
Reactome | mRNA Splicing | ||||
Reactome | mRNA Splicing - Major Pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Metabolism of RNA | ||||
Processing of Capped Intron-Containing Pre-mRNA | ||||
mRNA Splicing | ||||
mRNA Splicing - Major Pathway | ||||
Viral Interactions (0)
Gene Ontology Terms (4)
Functions (1)
Components (2)
Processes (1)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Disease Associations (null)
GWAS Traits (23)
Items per page:
1 – 5 of 23
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
reticulocyte measurement | 2 | 3 | 3 | 86.9 | |||||
mean platelet volume | 2 | 2 | 2 | 78.3 | |||||
low density lipoprotein cholesterol measurement | 3 | 2 | 3 | 73 | |||||
triglyceride measurement | 4 | 4 | 4 | 66.3 | |||||
red blood cell distribution width | 2 | 2 | 2 | 64.4 | |||||
Items per page:
1 – 5 of 23
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
reticulocyte measurement | 3 | 86.9 | |||||
mean platelet volume | 2 | 78.3 | |||||
low density lipoprotein cholesterol measurement | 3 | 73 | |||||
triglyceride measurement | 4 | 66.3 | |||||
red blood cell distribution width | 2 | 64.4 | |||||
Find similar targets by:
IDG Resources
Orthologs (12)
1 – 5 of 12
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Mouse | MGI:1915208 | 67958 | ||||||
Rat | RGD:1307882 | 315903 | ||||||
Dog | U2 snRNP associated SURP domain containing | VGNC:48033 | 477103 | |||||
Horse | U2 snRNP associated SURP domain containing | VGNC:24697 | 100051188 | |||||
Cow | U2 snRNP associated SURP domain containing | VGNC:36557 | 505019 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Dog | U2 snRNP associated SURP domain containing | |||||
Horse | U2 snRNP associated SURP domain containing | |||||
Cow | U2 snRNP associated SURP domain containing | |||||
Publication Statistics
PubMed Score 5.26
PubMed score by year
PubTator Score 0.45
PubTator score by year
Related Publications
Text Mined References (8)
GeneRif Annotations (1)
Items per page:
0 of 0
PMID | Year | Title |
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