U2SURP
U2 snRNP-associated SURP motif-containing protein
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
interacting protein | 1 | ||
transcription factor perturbation | 0.97 | ||
transcription factor binding site profile | 0.92 | ||
histone modification site profile | 0.86 | ||
co-expressed gene | 0.85 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism of RNA | ||||
Reactome | Processing of Capped Intron-Containing Pre-mRNA | ||||
Reactome | mRNA Splicing | ||||
Reactome | mRNA Splicing - Major Pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism of RNA | ||||
Processing of Capped Intron-Containing Pre-mRNA | ||||
mRNA Splicing | ||||
mRNA Splicing - Major Pathway | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
reticulocyte measurement | 2 | 3 | 3 | 86.9 | |||||
mean platelet volume | 2 | 2 | 2 | 78.3 | |||||
low density lipoprotein cholesterol measurement | 3 | 2 | 3 | 73 | |||||
triglyceride measurement | 4 | 4 | 4 | 66.3 | |||||
red blood cell distribution width | 2 | 2 | 2 | 64.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
reticulocyte measurement | 3 | 86.9 | |||||
mean platelet volume | 2 | 78.3 | |||||
low density lipoprotein cholesterol measurement | 3 | 73 | |||||
triglyceride measurement | 4 | 66.3 | |||||
red blood cell distribution width | 2 | 64.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:1915208 | 67958 | ||||||
Rat | RGD:1307882 | 315903 | ||||||
Dog | U2 snRNP associated SURP domain containing | VGNC:48033 | 477103 | |||||
Horse | U2 snRNP associated SURP domain containing | VGNC:24697 | 100051188 | |||||
Cow | U2 snRNP associated SURP domain containing | VGNC:36557 | 505019 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Dog | U2 snRNP associated SURP domain containing | |||||
Horse | U2 snRNP associated SURP domain containing | |||||
Cow | U2 snRNP associated SURP domain containing | |||||
PMID | Year | Title |
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