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Tbio
TUBGCP6
Gamma-tubulin complex component 6

Protein Summary
Description
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. The protein encoded by this gene is part of a large multisubunit complex required for microtubule nucleation at the centrosome. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000248846
  • ENSP00000248846
  • ENSG00000128159

Symbol
  • GCP6
  • KIAA1669
  • GCP6
  • GCP-6
  • MCCRP
  • MCCRP1
  • MCPHCR
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.81
interacting protein
0.64
transcription factor binding site profile
0.62
tissue sample
0.61
tissue
0.56


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.68   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 106   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.68   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 106   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (162)
TUBGCP5
Tbio
Novelty:  0.04863776
p_int:  0.999998367
p_ni:  0.000001632
p_wrong:  1e-9
Score:  0.996
Data Source:  BioPlex,STRINGDB
TUBG2
Tbio
Novelty:  0.14828466
p_int:  0.999991044
p_ni:  0.000008952
p_wrong:  4e-9
Score:  0.996
Data Source:  BioPlex,STRINGDB
MZT2B
Tdark
Novelty:  0.69469786
p_int:  0.999982151
p_ni:  0.000017847
p_wrong:  2e-9
Score:  0.997
Data Source:  BioPlex,STRINGDB
MZT1
Tdark
Novelty:  0.06713659
p_int:  0.999940655
p_ni:  0.000059345
Score:  0.999
Data Source:  BioPlex,STRINGDB
TXNDC12
Tbio
Novelty:  0.01354011
p_int:  0.999919276
p_ni:  0.000080724
Score:  0.819
Data Source:  BioPlex,STRINGDB
LGALS3BP
Tbio
Novelty:  0.0025302
p_int:  0.997791499
p_ni:  0.002208499
p_wrong:  2e-9
Score:  0.544
Data Source:  BioPlex,STRINGDB
BTRC
Tbio
Novelty:  0.00293475
p_int:  0.981456386
p_ni:  0.018543605
p_wrong:  9e-9
Data Source:  BioPlex
ZNF785
Tdark
Family:  TF
Novelty:  0.42629766
p_int:  0.905917517
p_ni:  0.094082482
p_wrong:  1e-9
Data Source:  BioPlex
IQCN
Tdark
Novelty:  2.74045479
p_int:  0.876564379
p_ni:  0.123435545
p_wrong:  7.6e-8
Data Source:  BioPlex
PRICKLE3
Tbio
Novelty:  0.26347141
p_int:  0.752948642
p_ni:  0.247051293
p_wrong:  6.4e-8
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (9)
Cell Cycle (R-HSA-1640170)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 9
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cell Cycle
Reactome
Cell Cycle, Mitotic
Reactome
Centrosome maturation
Reactome
G2/M Transition
Reactome
M Phase
Name
Explore in Pharos
Explore in Source
Cell Cycle
Cell Cycle, Mitotic
Centrosome maturation
G2/M Transition
M Phase
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (22)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
2
3
4
97.7
platelet crit
2
3
4
97.7
hematological measurement
1
1
1
80.4
mitochondrial DNA measurement
1
2
2
76.1
eosinophil count
2
1
2
68.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
4
97.7
platelet crit
4
97.7
hematological measurement
1
80.4
mitochondrial DNA measurement
2
76.1
eosinophil count
2
68.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
tubulin gamma complex associated protein 6
VGNC:12939
458986
Mouse
MGI:2146071
328580
Rat
RGD:1307743
362980
Dog
tubulin gamma complex associated protein 6
VGNC:47996
481193
Cow
tubulin gamma complex associated protein 6
VGNC:36516
618908
Species
Name
OMA
EggNOG
Inparanoid
Chimp
tubulin gamma complex associated protein 6
Mouse
Rat
Dog
tubulin gamma complex associated protein 6
Cow
tubulin gamma complex associated protein 6
Publication Statistics
PubMed Score 14.68
PubMed score by year
PubTator Score 4.41
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title