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Tbio
TUBGCP5
Gamma-tubulin complex component 5

Protein Summary
Description
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000615383
  • ENSP00000480316
  • ENSG00000275835
  • ENST00000620435
  • ENSP00000481853

Symbol
  • GCP5
  • KIAA1899
  • GCP5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.86
cellular component
0.78
kinase perturbation
0.71
cell line
0.65
transcription factor binding site profile
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.35   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 125   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.35   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 125   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (132)
TUBG2
Tbio
Novelty:  0.14828466
p_int:  1
Score:  0.989
Data Source:  BioPlex,STRINGDB
MZT2B
Tdark
Novelty:  0.69469786
p_int:  0.999999998
p_ni:  2e-9
Score:  0.998
Data Source:  BioPlex,STRINGDB
MZT1
Tdark
Novelty:  0.06713659
p_int:  0.999999567
p_ni:  4.32e-7
p_wrong:  1e-9
Score:  0.998
Data Source:  BioPlex,STRINGDB
TUBGCP6
Tbio
Novelty:  0.05801955
p_int:  0.999998367
p_ni:  0.000001632
p_wrong:  1e-9
Score:  0.996
Data Source:  BioPlex,STRINGDB
TUBGCP4
Tbio
Novelty:  0.04549455
p_int:  0.999991653
p_ni:  0.000008175
p_wrong:  1.72e-7
Score:  0.999
Data Source:  BioPlex,STRINGDB
TUBGCP3
Tbio
Novelty:  0.0221126
p_int:  0.999948615
p_ni:  0.000051385
Score:  0.995
Data Source:  BioPlex,STRINGDB
TXNDC12
Tbio
Novelty:  0.01354011
p_int:  0.999943078
p_ni:  0.000056904
p_wrong:  1.7e-8
Score:  0.859
Data Source:  BioPlex,STRINGDB
TUBGCP2
Tbio
Novelty:  0.01856674
p_int:  0.999852587
p_ni:  0.000147413
Score:  0.992
Data Source:  BioPlex,STRINGDB
MZT2A
Tdark
Novelty:  1.66535264
p_int:  0.99984909
p_ni:  4.7e-8
p_wrong:  0.000150863
Score:  0.996
Data Source:  BioPlex,STRINGDB
TUBG1
Tbio
Novelty:  0.02252882
p_int:  0.999603713
p_ni:  0.000396287
Score:  0.993
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (10)
Cell Cycle (R-HSA-1640170)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 9
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cell Cycle
Reactome
Cell Cycle, Mitotic
Reactome
Centrosome maturation
Reactome
G2/M Transition
Reactome
M Phase
Name
Explore in Pharos
Explore in Source
Cell Cycle
Cell Cycle, Mitotic
Centrosome maturation
G2/M Transition
M Phase
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
1
2
55.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
55.2
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2178836
233276
Rat
RGD:1304689
308663
Dog
tubulin gamma complex associated protein 5
VGNC:47995
478999
Horse
tubulin gamma complex associated protein 5
VGNC:24664
100147272
Cow
tubulin gamma complex associated protein 5
VGNC:36515
512912
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
tubulin gamma complex associated protein 5
Horse
tubulin gamma complex associated protein 5
Cow
tubulin gamma complex associated protein 5
Publication Statistics
PubMed Score 17.35
PubMed score by year
PubTator Score 6.80
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title