Tbio TUBD1 Tubulin delta chain

Protein Summary

Description

Acts as a positive regulator of hedgehog signaling and regulates ciliary function.

Uniprot Accession IDs

• Q9UJT1
• B4DPT8
• B4DW01
• D3DU02
• E9PCA7
• E9PCQ8
• Q5KU36
• Q9BWG9
• Q9H7Z8

Gene Name

• TUBD1

Ensembl ID

• ENST00000325752
• ENSP00000320797
• ENSG00000108423
• ENST00000340993
• ENSP00000342399
• ENST00000346141
• ENSP00000342561
• ENST00000376094
• ENSP00000365262
• ENST00000394239
• ENSP00000377785
• ENST00000539018
• ENSP00000441757
• ENST00000592426
• ENSP00000468518
• ENST00000613721
• ENSP00000480387

Symbol

• TUBD
• TUBD

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.93
histone modification site profile	0.9
protein domain	0.85
kinase perturbation	0.76
virus perturbation	0.76

Protein Classes

PANTHER Classes

Protein / Cytoskeletal Protein / Microtubule Family Cytoskeletal Protein / Tubulin / Tubulin Delta Chain

DTO Classes

Protein / Cellular Structure / Microtubule Family Cytoskeletal Protein / Tubulin / Tubulin Delta Chain

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28.92   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 117   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28.92   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 117   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0