Protein Summary
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
- ENST00000317702
- ENSP00000318697
- ENSG00000176014
- FPVEPD
- TUBB-5
- HsT1601
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
interacting protein | 1 | ||
protein complex | 1 | ||
protein domain | 0.97 | ||
disease perturbation | 0.96 | ||
virus perturbation | 0.96 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 20.75 (req: < 5)
Gene RIFs: 7 (req: <= 3)
Antibodies: 112 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 20.75 (req: >= 5)
Gene RIFs: 7 (req: > 3)
Antibodies: 112 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drugs: 13
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (13)
Active Ligands (0)
Protein-Protein Interactions (96)
Nearest Tclin Targets
Pathways (21)
Reactome (9)
KEGG (3)
PathwayCommons (2)
WikiPathways (7)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Carboxyterminal post-translational modifications of tubulin | ||||
Reactome | Chaperonin-mediated protein folding | ||||
Reactome | Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | ||||
Reactome | Formation of tubulin folding intermediates by CCT/TriC | ||||
Reactome | Metabolism of proteins | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Carboxyterminal post-translational modifications of tubulin | ||||
Chaperonin-mediated protein folding | ||||
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | ||||
Formation of tubulin folding intermediates by CCT/TriC | ||||
Metabolism of proteins | ||||
Viral Interactions (0)
Gene Ontology Terms (10)
Functions (3)
Components (4)
Processes (3)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Disease Associations ()
GWAS Traits (0)
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | tubulin beta 6 class V | VGNC:10010 | 455508 | |||||
Mouse | MGI:1915201 | 67951 | ||||||
Rat | RGD:1305887 | 307351 | ||||||
Dog | tubulin beta 6 class V | VGNC:47991 | 480213 | |||||
Horse | tubulin beta 6 class V | VGNC:50983 | 100058421 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | tubulin beta 6 class V | |||||
Mouse | ||||||
Rat | ||||||
Dog | tubulin beta 6 class V | |||||
Horse | tubulin beta 6 class V | |||||
Publication Statistics
PubMed Score 20.75
PubMed score by year
PubTator Score 7.77
PubTator score by year
Related Publications
Text Mined References (21)
GeneRif Annotations (7)
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