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Tclin
TUBB4B
Tubulin beta-4B chain

Protein Summary
Description
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000340384
  • ENSP00000341289
  • ENSG00000188229

Symbol
  • TUBB2C
  • Beta2
  • TUBB2
  • LCAEOD
  • TUBB2C
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
1
protein complex
1
molecular function
0.99
protein domain
0.97
transcription factor binding site profile
0.97


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.23   (req: < 5)
Gene RIFs: 11   (req: <= 3)
Antibodies: 134   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.23   (req: >= 5)
Gene RIFs: 11   (req: > 3)
Antibodies: 134   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 14
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drugs: 13