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Tdark
TTC9C
Tetratricopeptide repeat protein 9C

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000316461
  • ENSP00000325266
  • ENSG00000162222
  • ENST00000532583
  • ENSP00000434340
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.91
virus perturbation
0.88
transcription factor binding site profile
0.84
cell type or tissue
0.8
protein domain
0.73


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.94   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 98   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.94   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 98   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (94)
FBXO38
Tbio
Novelty:  0.06588101
p_int:  0.999999928
p_ni:  7.2e-8
Data Source:  BioPlex
NADSYN1
Tbio
Family:  Enzyme
Novelty:  0.0445844
p_int:  0.999999834
p_ni:  2e-8
p_wrong:  1.46e-7
Data Source:  BioPlex
FBXO10
Tbio
Novelty:  0.18324932
p_int:  0.999996866
p_ni:  0.000003134
Data Source:  BioPlex
FBH1
Tbio
Family:  Enzyme
Novelty:  0.04243458
p_int:  0.999995919
p_ni:  0.000003496
p_wrong:  5.85e-7
Data Source:  BioPlex
FAM172A
Tbio
Novelty:  0.1200899
p_int:  0.999995912
p_ni:  0.000004088
Data Source:  BioPlex
CUL7
Tbio
Novelty:  0.02183958
p_int:  0.999992926
p_ni:  0.000007075
Data Source:  BioPlex
FBXW2
Tbio
Novelty:  0.01492058
p_int:  0.999949095
p_ni:  0.000049814
p_wrong:  0.000001091
Data Source:  BioPlex
FBXL18
Tdark
Novelty:  0.33137957
p_int:  0.99993134
p_ni:  0.000068474
p_wrong:  1.86e-7
Data Source:  BioPlex
HSP90AA4P
Tdark
p_int:  0.999868983
p_ni:  0.000100114
p_wrong:  0.000030903
Data Source:  BioPlex
FBXL14
Tbio
Novelty:  0.21211079
p_int:  0.999849473
p_ni:  0.000150527
Score:  0.187
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
waist-hip ratio
1
4
4
84.9
BMI-adjusted waist-hip ratio
1
4
4
84
self reported educational attainment
1
1
1
63.7
mathematical ability
1
1
1
50.6
waist circumference
1
1
1
49.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
waist-hip ratio
4
84.9
BMI-adjusted waist-hip ratio
4
84
self reported educational attainment
1
63.7
mathematical ability
1
50.6
waist circumference
1
49.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
tetratricopeptide repeat domain 9C
VGNC:957
466638
Mouse
MGI:1917637
70387
Rat
RGD:1359253
309196
Dog
tetratricopeptide repeat domain 9C
VGNC:47966
483782
Horse
tetratricopeptide repeat domain 9C
VGNC:24638
100146759
Species
Name
OMA
EggNOG
Inparanoid
Chimp
tetratricopeptide repeat domain 9C
Mouse
Rat
Dog
tetratricopeptide repeat domain 9C
Horse
tetratricopeptide repeat domain 9C
Publication Statistics
PubMed Score 0.94
PubMed score by year
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Related Publications
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PMID
Year
Title