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Tdark
TSPYL6
Testis-specific Y-encoded-like protein 6

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.61   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 113   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.61   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 113   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (66)
HEATR1
Tbio
Novelty:  0.10365788
p_int:  0.999998194
p_ni:  0.000001806
Score:  0.175
Data Source:  BioPlex,STRINGDB
TSPYL2
Tbio
Novelty:  0.03720016
p_int:  0.999997988
p_ni:  0.000002012
Score:  0.173
Data Source:  BioPlex,STRINGDB
TUBB1
Tclin
Novelty:  0.02806117
p_int:  0.999995759
p_ni:  0.000004239
p_wrong:  2e-9
Data Source:  BioPlex
USP46
Tbio
Family:  Enzyme
Novelty:  0.04594593
p_int:  0.99998052
p_ni:  0.000019478
p_wrong:  2e-9
Score:  0.233
Data Source:  BioPlex,STRINGDB
USP12
Tbio
Family:  Enzyme
Novelty:  0.0460009
p_int:  0.999888128
p_ni:  0.000111865
p_wrong:  7e-9
Data Source:  BioPlex
WDR20
Tbio
Novelty:  0.03031804
p_int:  0.999879023
p_ni:  0.000120977
p_wrong:  1e-9
Score:  0.213
Data Source:  BioPlex,STRINGDB
DMXL2
Tbio
Novelty:  0.06848356
p_int:  0.999485528
p_ni:  0.000514439
p_wrong:  3.3e-8
Data Source:  BioPlex
KDM5B
Tchem
Family:  TF; Epigenetic
Novelty:  0.00610414
p_int:  0.998065865
p_ni:  0.000001897
p_wrong:  0.001932239
Score:  0.221
Data Source:  BioPlex,STRINGDB
DDX24
Tbio
Family:  Enzyme
Novelty:  0.17803446
p_int:  0.997061542
p_ni:  0.002938458
Score:  0.254
Data Source:  BioPlex,STRINGDB
AMER1
Tbio
Novelty:  0.00951499
p_int:  0.996476163
p_ni:  0.003523836
p_wrong:  1e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
2
2
86.8
glomerular filtration rate
3
2
2
6.2
82.8
telomere length
2
2
2
77
educational attainment
1
1
1
33.8
blood urea nitrogen measurement
1
1
1
18
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
86.8
glomerular filtration rate
2
6.2
82.8
telomere length
2
77
educational attainment
1
33.8
blood urea nitrogen measurement
1
18
IDG Resources
No IDG generated resources found
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
TSPY like 6
VGNC:48968
741018
Macaque
TSPY like 6
716697
Species
Name
OMA
EggNOG
Inparanoid
Chimp
TSPY like 6
Macaque
TSPY like 6
Publication Statistics
PubMed Score 1.61
PubMed score by year
PubTator Score 2.03
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title