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Tdark
TSPYL4
Testis-specific Y-encoded-like protein 4

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.95   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 128   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.95   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 128   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (31)
DFFA
Tbio
Novelty:  0.00253065
p_int:  0.999999933
p_ni:  6.7e-8
Score:  0.534
Data Source:  BioPlex,STRINGDB
MAGEA4
Tbio
Novelty:  0.00949096
p_int:  0.999999796
p_ni:  1.87e-7
p_wrong:  1.6e-8
Score:  0.663
Data Source:  BioPlex,STRINGDB
NAP1L5
Tbio
Novelty:  0.10378595
p_int:  0.999994384
p_ni:  0.000005604
p_wrong:  1.3e-8
Score:  0.484
Data Source:  BioPlex,STRINGDB
IFT74
Tbio
Novelty:  0.07195266
p_int:  0.999860605
p_ni:  0.000139395
Score:  0.179
Data Source:  BioPlex,STRINGDB
P4HA2
Tbio
Family:  Enzyme
Novelty:  0.02097718
p_int:  0.999815351
p_ni:  0.000088654
p_wrong:  0.000095995
Data Source:  BioPlex
DCAF8L2
Tdark
Novelty:  6.73057868
p_int:  0.999631086
p_ni:  0.000364265
p_wrong:  0.000004648
Data Source:  BioPlex
NF2
Tbio
Novelty:  0.00055092
p_int:  0.999576803
p_ni:  0.000422264
p_wrong:  9.32e-7
Score:  0.228
Data Source:  BioPlex,STRINGDB
TSPYL1
Tbio
Novelty:  0.06381144
p_int:  0.989896092
p_ni:  0.007437736
p_wrong:  0.002666173
Score:  0.4
Data Source:  BioPlex,STRINGDB
KLHDC3
Tdark
Novelty:  0.63840156
p_int:  0.882321342
p_ni:  0.002470731
p_wrong:  0.115207927
Data Source:  BioPlex
GABRD
Tclin
Family:  IC
Novelty:  0.0204242
Score:  0.675
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
1
1
1
44.2
electroencephalogram measurement
1
1
1
17.8
alcohol dependence measurement
1
1
1
17.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
1
44.2
electroencephalogram measurement
1
17.8
alcohol dependence measurement
1
17.8
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
TSPY like 4
VGNC:12738
462956
Mouse
MGI:106393
72480
Rat
RGD:1306653
309828
Dog
TSPY like 4
VGNC:47929
481973
Horse
TSPY like 4
VGNC:24600
100072645
Species
Name
OMA
EggNOG
Inparanoid
Chimp
TSPY like 4
Mouse
Rat
Dog
TSPY like 4
Horse
TSPY like 4
Publication Statistics
PubMed Score 1.95
PubMed score by year
PubTator Score 2.83
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title