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Tbio
TSPOAP1
Peripheral-type benzodiazepine receptor-associated protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000268893
  • ENSP00000268893
  • ENSG00000005379
  • ENST00000343736
  • ENSP00000345824

Symbol
  • BZRAP1
  • KIAA0612
  • RBP1
  • RIMBP1
  • PRAX1
  • BZRAP1
  • PBR-IP
  • PRAX-1
  • RIMBP1
  • RIM-BP1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.02   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 23   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.02   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 23   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (85)
CD244
Tbio
Novelty:  0.01137579
p_int:  0.813015569
p_ni:  0.000044661
p_wrong:  0.18693977
Score:  0.303
Data Source:  BioPlex,STRINGDB
RIMS1
Tbio
Novelty:  0.01126545
Score:  0.983
Data Source:  Reactome,STRINGDB
RIMS2
Tbio
Novelty:  0.02785894
Score:  0.983
Data Source:  STRINGDB
B1AH88
Tchem
Novelty:  0.00082324
Score:  0.976
Data Source:  STRINGDB
P30536
Tchem
Novelty:  0.00082324
Score:  0.976
Data Source:  Reactome,STRINGDB
UNC13B
Tbio
Novelty:  0.00429808
Score:  0.973
Data Source:  Reactome,STRINGDB
RAB3A
Tbio
Family:  Enzyme
Novelty:  0.0043532
Score:  0.969
Data Source:  STRINGDB
SYT1
Tbio
Novelty:  0.00176103
Score:  0.938
Data Source:  STRINGDB
PPFIA3
Tbio
Novelty:  0.03837299
Score:  0.935
Data Source:  Reactome,STRINGDB
PPFIA1
Tbio
Novelty:  0.01904029
Score:  0.933
Data Source:  Reactome,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (13)
Acetylcholine Neurotransmitter Release Cycle (R-HSA-264642)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 13
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Acetylcholine Neurotransmitter Release Cycle
Reactome
Dopamine Neurotransmitter Release Cycle
Reactome
Glutamate Neurotransmitter Release Cycle
Reactome
Metabolism
Reactome
Metabolism of lipids
Name
Explore in Pharos
Explore in Source
Acetylcholine Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Metabolism
Metabolism of lipids
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (29)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte percentage of leukocytes
2
7
8
98.6
neutrophil count
2
4
4
96.5
myeloperoxidase measurement
2
3
3
95.8
neutrophil percentage of leukocytes
2
4
5
93.4
leukocyte count
2
3
3
93.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte percentage of leukocytes
8
98.6
neutrophil count
4
96.5
myeloperoxidase measurement
3
95.8
neutrophil percentage of leukocytes
5
93.4
leukocyte count
3
93.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
TSPO associated protein 1
VGNC:9154
455154
Macaque
TSPO associated protein 1
714301
Mouse
MGI:2450877
207777
Rat
RGD:708563
287609
Dog
TSPO associated protein 1
VGNC:47927
491112
Species
Name
OMA
EggNOG
Inparanoid
Chimp
TSPO associated protein 1
Macaque
TSPO associated protein 1
Mouse
Rat
Dog
TSPO associated protein 1
Publication Statistics
PubMed Score 10.02
PubMed score by year
PubTator Score 5.12
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title