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Tdark
TSPAN11
Tetraspanin-11

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000261177
  • ENSP00000261177
  • ENSG00000110900
  • ENST00000546076
  • ENSP00000437403

Symbol
  • VSSW1971
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.77
cell line
0.69
trait
0.61
histone modification site profile
0.6
tissue sample
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.74   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 26   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.74   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 26   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (35)
POMC
Tbio
Novelty:  0.00002436
p_int:  0.999999849
p_ni:  1.45e-7
p_wrong:  6e-9
Score:  0.187
Data Source:  BioPlex,STRINGDB
ITGA6
Tbio
Novelty:  0.00217985
p_int:  0.999972664
p_ni:  0.000027336
Score:  0.211
Data Source:  BioPlex,STRINGDB
ITGA7
Tbio
Novelty:  0.01243073
p_int:  0.999800575
p_ni:  0.000199425
Score:  0.282
Data Source:  BioPlex,STRINGDB
ESYT1
Tbio
Novelty:  0.03069611
p_int:  0.99934484
p_ni:  0.00065516
Score:  0.318
Data Source:  BioPlex,STRINGDB
CYB5R3
Tbio
Family:  Enzyme
Novelty:  0.00774258
p_int:  0.977395435
p_ni:  0.022604564
p_wrong:  1e-9
Score:  0.186
Data Source:  BioPlex,STRINGDB
IGLL5
Tbio
Novelty:  0.00459259
p_int:  0.968702038
p_ni:  0.029635891
p_wrong:  0.001662071
Score:  0.177
Data Source:  BioPlex,STRINGDB
NRP2
Tbio
Novelty:  0.00764179
p_int:  0.936551964
p_ni:  0.063445861
p_wrong:  0.000002175
Score:  0.2
Data Source:  BioPlex,STRINGDB
ARL6IP5
Tbio
Novelty:  0.00871985
p_int:  0.865502073
p_ni:  0.134497926
p_wrong:  1e-9
Data Source:  BioPlex
ITGB1
Tclin
Novelty:  0.00055626
p_int:  0.857073632
p_ni:  0.142926368
Score:  0.206
Data Source:  BioPlex,STRINGDB
REEP5
Tbio
Novelty:  0.00160455
p_int:  0.797898185
p_ni:  0.202101338
p_wrong:  4.77e-7
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
optic disc size measurement
1
1
1
17.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
optic disc size measurement
1
17.1
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
tetraspanin 11
694030
Mouse
MGI:1915748
68498
Rat
RGD:1305424
312727
Dog
tetraspanin 11
VGNC:47911
611819
Horse
tetraspanin 11
VGNC:24587
100051003
Species
Name
OMA
EggNOG
Inparanoid
Macaque
tetraspanin 11
Mouse
Rat
Dog
tetraspanin 11
Horse
tetraspanin 11
Publication Statistics
PubMed Score 1.74
PubMed score by year
PubTator Score 0.05
PubTator score by year
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Related Publications
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PMID
Year
Title