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Tbio
TSHZ1
Teashirt homolog 1

Protein Summary
Description
Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential). This gene encodes a colon cancer antigen that was defined by serological analysis of recombinant cDNA expression libraries. The encoded protein is a member of the teashirt C2H2-type zinc-finger protein family and may be involved in transcriptional regulation of developmental processes. Mutations in this gene may be associated with congenital aural atresia syndrome. [provided by RefSeq, Jan 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000322038
  • ENSP00000323584
  • ENSG00000179981
  • ENST00000580243
  • ENSP00000464391

Symbol
  • SDCCAG33
  • TSH1
  • CAA
  • TSH1
  • NY-CO-33
  • SDCCAG33
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.81
transcription factor binding site profile
0.81
transcription factor perturbation
0.8
cell type or tissue
0.79
PubMedID
0.78


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 132.68   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 163   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 132.68   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 163   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (54)
GLYAT
Tbio
Family:  Enzyme
Novelty:  0.02347543
Score:  0.86
Data Source:  STRINGDB
GAA
Tclin
Family:  Enzyme
Novelty:  0.0063246
Score:  0.86
Data Source:  STRINGDB
GGCT
Tchem
Family:  Enzyme
Novelty:  0.01154389
Score:  0.839
Data Source:  STRINGDB
AGA
Tbio
Family:  Enzyme
Novelty:  0.01522819
Score:  0.837
Data Source:  STRINGDB
GUCY2C
Tclin
Family:  Kinase
Novelty:  0.00209733
Score:  0.837
Data Source:  STRINGDB
GCA
Tbio
Novelty:  0.01485875
Score:  0.836
Data Source:  STRINGDB
FLVCR2
Tbio
Novelty:  0.02871146
Score:  0.817
Data Source:  STRINGDB
DOCK11
Tdark
Novelty:  0.0295159
Score:  0.8
Data Source:  STRINGDB
MPG
Tchem
Family:  Enzyme
Novelty:  0.00373538
Score:  0.797
Data Source:  STRINGDB
PCYT1A
Tchem
Family:  Enzyme
Novelty:  0.00621528
Score:  0.796
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (10)
Find Similar Targets
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (16)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
brain volume measurement
5
3
5
71.2
platelet count
2
2
2
64.5
vascular endothelial growth factor measurement
1
1
1
62.7
educational attainment
1
2
2
51.6
diastolic blood pressure
1
1
1
37.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
brain volume measurement
5
71.2
platelet count
2
64.5
vascular endothelial growth factor measurement
1
62.7
educational attainment
2
51.6
diastolic blood pressure
1
37.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
teashirt zinc finger homeobox 1
VGNC:13294
455478
Macaque
teashirt zinc finger homeobox 1
703018
Mouse
MGI:1346031
110796
Rat
Dog
teashirt zinc finger homeobox 1
VGNC:47903
102152070
Species
Name
OMA
EggNOG
Inparanoid
Chimp
teashirt zinc finger homeobox 1
Macaque
teashirt zinc finger homeobox 1
Mouse
Rat
Dog
teashirt zinc finger homeobox 1
Publication Statistics
PubMed Score 132.68
PubMed score by year
PubTator Score 90.16
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title