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Tbio
TSACC
TSSK6-activating co-chaperone protein

Protein Summary
Description
Co-chaperone that facilitates HSP-mediated activation of TSSK6.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000368251
  • ENSP00000357234
  • ENSG00000163467
  • ENST00000368252
  • ENSP00000357235
  • ENST00000368253
  • ENSP00000357236
  • ENST00000368254
  • ENSP00000357237
  • ENST00000368255
  • ENSP00000357238

Symbol
  • C1orf182
  • SIP
  • SSTK-IP
  • C1orf182
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.92
transcription factor binding site profile
0.75
cell type or tissue
0.54
cell line
0.49
tissue sample
0.46


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.07   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 53   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.07   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 53   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (41)
SNCB
Tbio
Novelty:  0.00743454
Score:  0.684
Data Source:  STRINGDB
ALKBH7
Tbio
Family:  Enzyme
Novelty:  0.12865849
Score:  0.673
Data Source:  STRINGDB
RIMBP3C
Tdark
Novelty:  12.18975991
Score:  0.647
Data Source:  STRINGDB
C2CD6
Tdark
Novelty:  1.30543834
Score:  0.606
Data Source:  STRINGDB
SLC25A51
Tbio
Family:  Transporter
Novelty:  0.21568087
Score:  0.6
Data Source:  STRINGDB
RIMBP3B
Tdark
Novelty:  0.78518303
Score:  0.595
Data Source:  STRINGDB
ARMC12
Tdark
Novelty:  1.14292403
Score:  0.59
Data Source:  STRINGDB
FAAP24
Tbio
Novelty:  0.08081633
Score:  0.563
Data Source:  STRINGDB
ANKRD7
Tdark
Novelty:  0.55891937
Score:  0.562
Data Source:  STRINGDB
C22orf23
Tdark
Novelty:  0.11734709
Score:  0.56
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Physical Interaction (IPI)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (16)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
HbA1c measurement
5
5
5
97.6
mean corpuscular hemoglobin concentration
5
5
5
93.2
mean corpuscular volume
2
2
2
80.7
erythrocyte count
2
2
2
77.3
hemoglobin measurement
2
2
2
69.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
HbA1c measurement
5
97.6
mean corpuscular hemoglobin concentration
5
93.2
mean corpuscular volume
2
80.7
erythrocyte count
2
77.3
hemoglobin measurement
2
69.2
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
TSSK6 activating cochaperone
VGNC:7018
457393
Mouse
MGI:1924177
76927
Rat
RGD:1304953
361979
Horse
TSSK6 activating cochaperone
VGNC:50900
100629772
Cow
TSSK6 activating cochaperone
VGNC:36406
767912
Species
Name
OMA
EggNOG
Inparanoid
Chimp
TSSK6 activating cochaperone
Mouse
Rat
Horse
TSSK6 activating cochaperone
Cow
TSSK6 activating cochaperone
Publication Statistics
PubMed Score 5.07
PubMed score by year
PubTator Score 3.92
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title