TRPC3
Short transient receptor potential channel 3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.92 | ||
molecular function | 0.9 | ||
hub protein | 0.82 | ||
metabolite | 0.82 | ||
biological process | 0.72 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Axon guidance | ||||
Reactome | Developmental Biology | ||||
Reactome | Effects of PIP2 hydrolysis | ||||
Reactome | Elevation of cytosolic Ca2+ levels | ||||
Reactome | G alpha (q) signalling events | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Axon guidance | ||||
Developmental Biology | ||||
Effects of PIP2 hydrolysis | ||||
Elevation of cytosolic Ca2+ levels | ||||
G alpha (q) signalling events | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | Reactome | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean corpuscular hemoglobin concentration | 2 | 2 | 2 | 93.8 | |||||
mean corpuscular volume | 2 | 2 | 2 | 87.2 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 85.1 | |||||
1 | 1 | 1 | 71.5 | ||||||
BMI-adjusted hip circumference | 1 | 3 | 3 | 66.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean corpuscular hemoglobin concentration | 2 | 93.8 | |||||
mean corpuscular volume | 2 | 87.2 | |||||
mean reticulocyte volume | 1 | 85.1 | |||||
1 | 71.5 | ||||||
BMI-adjusted hip circumference | 3 | 66.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | transient receptor potential cation channel subfamily C member 3 | VGNC:7428 | 471294 | |||||
Macaque | transient receptor potential cation channel subfamily C member 3 | 707586 | ||||||
Mouse | MGI:109526 | 22065 | ||||||
Rat | RGD:61973 | 60395 | ||||||
Dog | transient receptor potential cation channel subfamily C member 3 | VGNC:47867 | 483844 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | transient receptor potential cation channel subfamily C member 3 | |||||
Macaque | transient receptor potential cation channel subfamily C member 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | transient receptor potential cation channel subfamily C member 3 | |||||
PMID | Year | Title |
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