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Tbio
TROVE2
60 kDa SS-A/Ro ribonucleoprotein

Protein Summary
Description
RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation. May play roles in cilia formation and/or maintenance.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000367441
  • ENSP00000356411
  • ENSG00000116747
  • ENST00000367443
  • ENSP00000356413
  • ENST00000367444
  • ENSP00000356414
  • ENST00000367445
  • ENSP00000356415
  • ENST00000367446
  • ENSP00000356416
  • ENST00000400968
  • ENSP00000383752

Symbol
  • RO60
  • SSA2
  • SSA2
  • RORNP
  • TROVE2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
hub protein
1
virus perturbation
0.99
kinase perturbation
0.93
interacting protein
0.91
disease perturbation
0.9


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 393.88   (req: < 5)
Gene RIFs: 16   (req: <= 3)
Antibodies: 338   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 393.88   (req: >= 5)
Gene RIFs: 16   (req: > 3)
Antibodies: 338   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0