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Tbio
TROAP
Tastin

Protein Summary
Description
Could be involved with bystin and trophinin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000257909
  • ENSP00000257909
  • ENSG00000135451
  • ENST00000380327
  • ENSP00000369684
  • ENST00000548311
  • ENSP00000448313

Symbol
  • TASTIN
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.93
PubMedID
0.89
kinase perturbation
0.84
transcription factor perturbation
0.74
virus perturbation
0.72


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.46   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 72   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.46   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 72   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (140)
DCAF7
Tbio
Novelty:  0.02609518
p_int:  0.999999532
p_ni:  4.67e-7
Score:  0.168
Data Source:  BioPlex,STRINGDB
FANCD2OS
Tdark
Novelty:  9.51798561
p_int:  0.999991623
p_ni:  0.000008364
p_wrong:  1.4e-8
Data Source:  BioPlex
LZTS2
Tbio
Novelty:  0.09515452
p_int:  0.999873961
p_ni:  0.000126039
Data Source:  BioPlex
BANP
Tbio
Novelty:  0.02145545
p_int:  0.999638942
p_ni:  0.000358081
p_wrong:  0.000002978
Data Source:  BioPlex
FNTB
Tclin
Family:  Enzyme
Novelty:  0.07434994
p_int:  0.99959028
p_ni:  0.00040972
Score:  0.169
Data Source:  BioPlex,STRINGDB
PPP2R3A
Tbio
Family:  Enzyme
Novelty:  0.0350873
p_int:  0.997629613
p_ni:  0.002369707
p_wrong:  6.81e-7
Score:  0.186
Data Source:  BioPlex,STRINGDB
CDC16
Tbio
Novelty:  0.00916715
p_int:  0.995225421
p_ni:  0.004774474
p_wrong:  1.05e-7
Data Source:  BioPlex
ASB3
Tbio
Novelty:  0.15921018
p_int:  0.994495921
p_ni:  0.004304803
p_wrong:  0.001199276
Data Source:  BioPlex
CCNJL
Tdark
Novelty:  2.86306774
p_int:  0.991306599
p_ni:  0.008688139
p_wrong:  0.000005262
Score:  0.189
Data Source:  BioPlex,STRINGDB
LYPD4
Tbio
Novelty:  0.00381728
p_int:  0.976743382
p_ni:  0.021919757
p_wrong:  0.00133686
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
ProtInc
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
3
2
3
80.5
nerve conduction amplitude
1
1
1
72.8
platelet count
2
2
2
71.5
bone density
1
1
2
56.1
4
1
0
1.1
42.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
3
80.5
nerve conduction amplitude
1
72.8
platelet count
2
71.5
bone density
2
56.1
0
1.1
42.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
trophinin associated protein
VGNC:5639
451878
Macaque
trophinin associated protein
709931
Mouse
MGI:1925983
78733
Rat
RGD:1306870
300219
Dog
trophinin associated protein
VGNC:47863
608844
Species
Name
OMA
EggNOG
Inparanoid
Chimp
trophinin associated protein
Macaque
trophinin associated protein
Mouse
Rat
Dog
trophinin associated protein
Publication Statistics
PubMed Score 21.46
PubMed score by year
PubTator Score 11.83
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title