TRIP12
E3 ubiquitin-protein ligase TRIP12
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 1 | ||
virus perturbation | 1 | ||
interacting protein | 0.89 | ||
disease perturbation | 0.87 | ||
transcription factor binding site profile | 0.85 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Adaptive Immune System | ||||
Reactome | Antigen processing: Ubiquitination & Proteasome degradation | ||||
Reactome | Class I MHC mediated antigen processing & presentation | ||||
Reactome | Immune System | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Adaptive Immune System | ||||
Antigen processing: Ubiquitination & Proteasome degradation | ||||
Class I MHC mediated antigen processing & presentation | ||||
Immune System | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
body mass index | 2 | 1 | 2 | 68.6 | |||||
body height | 1 | 1 | 1 | 56.4 | |||||
systolic blood pressure | 1 | 1 | 1 | 46.5 | |||||
waist-hip ratio | 1 | 1 | 1 | 42.3 | |||||
glomerular filtration rate | 2 | 2 | 1 | 5.9 | 31.1 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
body mass index | 2 | 68.6 | |||||
body height | 1 | 56.4 | |||||
systolic blood pressure | 1 | 46.5 | |||||
waist-hip ratio | 1 | 42.3 | |||||
glomerular filtration rate | 1 | 5.9 | 31.1 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | thyroid hormone receptor interactor 12 | VGNC:2894 | 459994 | |||||
Mouse | MGI:1309481 | 14897 | ||||||
Rat | RGD:1306607 | 316575 | ||||||
Dog | thyroid hormone receptor interactor 12 | VGNC:47845 | 477400 | |||||
Horse | thyroid hormone receptor interactor 12 | VGNC:49287 | 100056934 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | thyroid hormone receptor interactor 12 | |||||
Mouse | ||||||
Rat | ||||||
Dog | thyroid hormone receptor interactor 12 | |||||
Horse | thyroid hormone receptor interactor 12 | |||||
PMID | Year | Title |
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