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Tbio
TRAK2
Trafficking kinesin-binding protein 2

Protein Summary
Description
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000332624
  • ENSP00000328875
  • ENSG00000115993
  • ENST00000430254
  • ENSP00000409333

Symbol
  • ALS2CR3
  • KIAA0549
  • GRIF1
  • MILT2
  • OIP98
  • CALS-C
  • GRIF-1
  • ALS2CR3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.92
histone modification site profile
0.81
transcription factor perturbation
0.8
transcription factor binding site profile
0.77
cell line
0.68


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.55   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 229   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.55   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 229   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 19
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0