TRA2A
Transformer-2 protein homolog alpha
Protein Summary
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]
- ENST00000297071
- ENSP00000297071
- ENSG00000164548
- ENST00000392502
- ENSP00000376290
- ENST00000538367
- ENSP00000441116
- ENST00000621813
- ENSP00000480822
- AWMS1
- HSU53209
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
interacting protein | 0.89 | ||
transcription factor binding site profile | 0.84 | ||
ligand (protein) perturbation | 0.83 | ||
drug perturbation | 0.71 | ||
transcription factor perturbation | 0.68 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 24.08 (req: < 5)
Gene RIFs: 6 (req: <= 3)
Antibodies: 161 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 24.08 (req: >= 5)
Gene RIFs: 6 (req: > 3)
Antibodies: 161 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0