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Tbio
TRA2A
Transformer-2 protein homolog alpha

Protein Summary
Description
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000297071
  • ENSP00000297071
  • ENSG00000164548
  • ENST00000392502
  • ENSP00000376290
  • ENST00000538367
  • ENSP00000441116
  • ENST00000621813
  • ENSP00000480822

Symbol
  • AWMS1
  • HSU53209
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.89
transcription factor binding site profile
0.84
ligand (protein) perturbation
0.83
drug perturbation
0.71
transcription factor perturbation
0.68


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.08   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 161   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.08   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 161   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0