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Tbio
TP53I11
Tumor protein p53-inducible protein 11

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000308212
  • ENSP00000309532
  • ENSG00000175274
  • ENST00000395648
  • ENSP00000379009
  • ENST00000525680
  • ENSP00000433474
  • ENST00000533940
  • ENSP00000436152
  • ENST00000616990
  • ENSP00000481456

Symbol
  • PIG11
  • PIG11
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
small molecule perturbation
0.71
tissue
0.59
transcription factor binding site profile
0.55
tissue sample
0.51
transcription factor
0.51


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.83   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 161   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.83   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 161   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (21)
MANSC1
Tdark
Novelty:  0.91681036
p_int:  0.999995546
p_ni:  0.000004397
p_wrong:  5.7e-8
Score:  0.181
Data Source:  BioPlex,STRINGDB
YIPF3
Tbio
Novelty:  0.12021667
p_int:  0.847677233
p_ni:  0.000143123
p_wrong:  0.152179644
Score:  0.181
Data Source:  BioPlex,STRINGDB
TXNL1
Tbio
Novelty:  0.01151931
Score:  0.649
Data Source:  STRINGDB
ARFGEF1
Tbio
Novelty:  0.16148196
Score:  0.628
Data Source:  STRINGDB
TP53INP2
Tbio
Novelty:  0.03156719
Score:  0.575
Data Source:  STRINGDB
WBP2
Tbio
Novelty:  0.05612455
Score:  0.538
Data Source:  STRINGDB
TP53
Tchem
Family:  TF
Novelty:  0.00001907
Score:  0.528
Data Source:  STRINGDB
ENDOD1
Tdark
Family:  Enzyme
Novelty:  0.26430864
Score:  0.522
Data Source:  STRINGDB
PHLDA2
Tbio
Novelty:  0.01847579
Score:  0.494
Data Source:  STRINGDB
EFCAB10
Tdark
Novelty:  17.37931034
Score:  0.492
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.3
50.6
brain measurement
1
1
0
274.1
24.5
intraocular pressure measurement
1
1
1
17.8
reaction time measurement
1
2
2
7.8
smoking status measurement
1
1
0
11.7
3.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.3
50.6
brain measurement
0
274.1
24.5
intraocular pressure measurement
1
17.8
reaction time measurement
2
7.8
smoking status measurement
0
11.7
3.1
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
tumor protein p53 inducible protein 11
VGNC:13316
743617
Mouse
MGI:2670995
277414
Rat
RGD:1308395
311209
Dog
tumor protein p53 inducible protein 11
VGNC:47722
483645
Horse
tumor protein p53 inducible protein 11
VGNC:24420
100050141
Species
Name
OMA
EggNOG
Inparanoid
Chimp
tumor protein p53 inducible protein 11
Mouse
Rat
Dog
tumor protein p53 inducible protein 11
Horse
tumor protein p53 inducible protein 11
Publication Statistics
PubMed Score 4.83
PubMed score by year
PubTator Score 6.31
PubTator score by year
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Related Publications
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PMID
Year
Title