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Tbio
TOX4
TOX high mobility group box family member 4

Protein Summary
Description
Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000448790
  • ENSP00000393080
  • ENSG00000092203
  • ENST00000613569
  • ENSP00000477868

Symbol
  • C14orf92
  • KIAA0737
  • LCP1
  • MIG7
  • C14orf92
  • KIAA0737
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
1
histone modification site profile
0.91
transcription factor perturbation
0.88
ligand (protein) perturbation
0.83
transcription factor binding site profile
0.81


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 63.75   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 120   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 63.75   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 120   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0