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Tbio
TOMM6
Mitochondrial import receptor subunit TOM6 homolog

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000398881
  • ENSP00000381856
  • ENSG00000214736
  • ENST00000398884
  • ENSP00000381859

Symbol
  • OBTP
  • TOM6
  • OBTP
  • TOM6
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
small molecule perturbation
0.95
transcription factor binding site profile
0.88
histone modification site profile
0.73
cell type or tissue
0.66
tissue
0.59


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.29   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 68   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.29   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 68   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (59)
TOMM5
Tdark
Novelty:  0.07962801
Score:  0.989
Data Source:  STRINGDB
TOMM7
Tbio
Novelty:  0.03885154
Score:  0.986
Data Source:  STRINGDB
TOMM22
Tbio
Novelty:  0.01217913
Score:  0.981
Data Source:  STRINGDB
TOMM70
Tbio
Novelty:  0.00943973
Score:  0.979
Data Source:  STRINGDB
TOMM40
Tbio
Novelty:  0.0041507
Score:  0.978
Data Source:  STRINGDB
TOMM20
Tbio
Novelty:  0.00275824
Score:  0.971
Data Source:  STRINGDB
HSPA9
Tchem
Novelty:  0.00235171
Score:  0.939
Data Source:  STRINGDB
ATP5MC1
Tbio
Family:  Enzyme
Novelty:  0.03538978
Score:  0.912
Data Source:  STRINGDB
TIMM22
Tbio
Family:  Enzyme
Novelty:  0.12627933
Score:  0.91
Data Source:  STRINGDB
CYC1
Tchem
Novelty:  0.01369865
Score:  0.905
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (7)
Autophagy (R-HSA-9612973)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 7
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Autophagy
Reactome
Cellular responses to external stimuli
Reactome
Macroautophagy
Reactome
Mitochondrial protein import
Reactome
Mitophagy
Name
Explore in Pharos
Explore in Source
Autophagy
Cellular responses to external stimuli
Macroautophagy
Mitochondrial protein import
Mitophagy
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (23)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
6
5
5
5.5
93.9
sex hormone-binding globulin measurement
9
2
8
9.1
91.7
mean corpuscular volume
2
3
3
85.9
mean reticulocyte volume
1
2
2
84.5
BMI-adjusted waist-hip ratio
2
1
2
74
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
5
5.5
93.9
sex hormone-binding globulin measurement
8
9.1
91.7
mean corpuscular volume
3
85.9
mean reticulocyte volume
2
84.5
BMI-adjusted waist-hip ratio
2
74
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
translocase of outer mitochondrial membrane 6
VGNC:13151
748580
Mouse
MGI:1913369
66119
Rat
RGD:1583567
681123
Dog
translocase of outer mitochondrial membrane 6
VGNC:49103
609079
Horse
translocase of outer mitochondrial membrane 6
VGNC:50514
100629249
Species
Name
OMA
EggNOG
Inparanoid
Chimp
translocase of outer mitochondrial membrane 6
Mouse
Rat
Dog
translocase of outer mitochondrial membrane 6
Horse
translocase of outer mitochondrial membrane 6
Publication Statistics
PubMed Score 9.29
PubMed score by year
PubTator Score 4.37
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title