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Tbio
TOM1L1
TOM1-like protein 1

Protein Summary
Description
Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000348161
  • ENSP00000343901
  • ENSG00000141198
  • ENST00000536554
  • ENSP00000443099
  • ENST00000570371
  • ENSP00000458553
  • ENST00000575333
  • ENSP00000458918
  • ENST00000575882
  • ENSP00000460823

Symbol
  • SRCASM
  • SRCASM
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.92
protein domain
0.85
transcription factor perturbation
0.84
histone modification site profile
0.77
biological process
0.71


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.52   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 229   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.52   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 229   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 11
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0