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Tdark
TNRC18
Trinucleotide repeat-containing gene 18 protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000430969
  • ENSP00000395538
  • ENSG00000182095

Symbol
  • CAGL79
  • KIAA1856
  • CAGL79
  • TNRC18A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.88
transcription factor perturbation
0.8
cellular component
0.75
cell type or tissue
0.72
kinase perturbation
0.71


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.79   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 25   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.79   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 25   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (58)
DAXX
Tbio
Novelty:  0.00348585
p_int:  0.999999028
p_ni:  9.72e-7
Data Source:  BioPlex
SINHCAF
Tdark
Novelty:  0.18692832
p_int:  0.999998895
p_ni:  0.000001105
Score:  0.176
Data Source:  BioPlex,STRINGDB
HDAC1
Tclin
Family:  Epigenetic
Novelty:  0.00065244
p_int:  0.999996824
p_ni:  0.000003176
Score:  0.588
Data Source:  BioPlex,STRINGDB
MDK
Tchem
Novelty:  0.00145301
p_int:  0.999886046
p_ni:  0.000113954
Score:  0.186
Data Source:  BioPlex,STRINGDB
RNF151
Tdark
Novelty:  2.0077961
p_int:  0.999869507
p_ni:  0.000130445
p_wrong:  4.8e-8
Data Source:  BioPlex
PRDM5
Tbio
Family:  TF; Epigenetic
Novelty:  0.01689997
p_int:  0.999830216
p_ni:  0.000169759
p_wrong:  2.5e-8
Score:  0.194
Data Source:  BioPlex,STRINGDB
EPB41L3
Tbio
Novelty:  0.00915217
p_int:  0.999733166
p_ni:  0.000266834
Data Source:  BioPlex
PES1
Tbio
Novelty:  0.07162845
p_int:  0.999505601
p_ni:  0.000494399
Data Source:  BioPlex
EPB41L1
Tbio
Novelty:  0.02937451
p_int:  0.994654308
p_ni:  0.005345666
p_wrong:  2.5e-8
Score:  0.221
Data Source:  BioPlex,STRINGDB
EDA
Tbio
Novelty:  0.00352464
p_int:  0.982926551
p_ni:  0.017073433
p_wrong:  1.6e-8
Score:  0.196
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (6)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations ()
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell density measurement
1
1
1
73.9
mean platelet volume
2
2
2
68.5
reticulocyte count
1
2
2
68.5
monocyte percentage of leukocytes
1
1
1
57.3
body mass index
1
1
1
40.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell density measurement
1
73.9
mean platelet volume
2
68.5
reticulocyte count
2
68.5
monocyte percentage of leukocytes
1
57.3
body mass index
1
40.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:3648294
231861
Rat
RGD:1307540
304302
Dog
trinucleotide repeat containing 18
VGNC:47698
489882
Cow
trinucleotide repeat containing 18
VGNC:36203
526616
Opossum
trinucleotide repeat-containing gene 18 protein
100014518
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
trinucleotide repeat containing 18
Cow
trinucleotide repeat containing 18
Opossum
trinucleotide repeat-containing gene 18 protein
Publication Statistics
PubMed Score 2.79
PubMed score by year
PubTator Score 0.14
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title