TNFRSF11A
Tumor necrosis factor receptor superfamily member 11A
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.97 | ||
biological term | 0.92 | ||
virus perturbation | 0.88 | ||
disease | 0.75 | ||
phenotype | 0.71 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | Immune System | ||||
Reactome | TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | ||||
Reactome | TNFR2 non-canonical NF-kB pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cytokine Signaling in Immune system | ||||
Immune System | ||||
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | ||||
TNFR2 non-canonical NF-kB pathway | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 3 | 2 | 6 | 91.6 | |||||
alkaline phosphatase measurement | 2 | 1 | 1 | 14.5 | 83.7 | ||||
2 | 2 | 0 | 1.5 | 76.8 | |||||
bone density | 5 | 2 | 7 | 70.5 | |||||
serum albumin measurement | 2 | 2 | 3 | 61.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 6 | 91.6 | |||||
alkaline phosphatase measurement | 1 | 14.5 | 83.7 | ||||
0 | 1.5 | 76.8 | |||||
bone density | 7 | 70.5 | |||||
serum albumin measurement | 3 | 61.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | TNF receptor superfamily member 11a | VGNC:5213 | 468560 | |||||
Mouse | MGI:1314891 | 21934 | ||||||
Rat | RGD:1563614 | 498206 | ||||||
Dog | TNF receptor superfamily member 11a | VGNC:47654 | 483957 | |||||
Horse | TNF receptor superfamily member 11a | VGNC:50982 | 100056617 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | TNF receptor superfamily member 11a | |||||
Mouse | ||||||
Rat | ||||||
Dog | TNF receptor superfamily member 11a | |||||
Horse | TNF receptor superfamily member 11a | |||||
PMID | Year | Title |
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