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Tdark
TMEM92
Transmembrane protein 92

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000300433
  • ENSP00000300433
  • ENSG00000167105
  • ENST00000507382
  • ENSP00000425144
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.85
microRNA
0.6
cell line
0.58
transcription factor
0.57
tissue
0.43


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.45   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 9   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.45   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 9   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (27)
WWOX
Tbio
Family:  Enzyme
Novelty:  0.00335243
p_int:  0.999909042
p_ni:  0.000090958
Score:  0.177
Data Source:  BioPlex,STRINGDB
NEDD4L
Tbio
Family:  Enzyme
Novelty:  0.00250567
p_int:  0.9989361
p_ni:  0.0010639
Score:  0.217
Data Source:  BioPlex,STRINGDB
NEDD4
Tchem
Family:  Enzyme
Novelty:  0.00281725
p_int:  0.994525199
p_ni:  0.005474801
Score:  0.282
Data Source:  BioPlex,STRINGDB
POMT2
Tbio
Family:  Enzyme
Novelty:  0.0251595
p_int:  0.953800894
p_ni:  0.046199106
Score:  0.167
Data Source:  BioPlex,STRINGDB
HBB
Tbio
Novelty:  0.00049683
p_int:  0.910825144
p_ni:  0.089174856
Data Source:  BioPlex
CUEDC1
Tbio
Novelty:  0.14401061
p_int:  0.892561389
p_ni:  0.107438568
p_wrong:  4.3e-8
Score:  0.169
Data Source:  BioPlex,STRINGDB
ITCH
Tbio
Family:  Enzyme
Novelty:  0.00681861
p_int:  0.886694098
p_ni:  0.113305902
Score:  0.215
Data Source:  BioPlex,STRINGDB
POMT1
Tbio
Family:  Enzyme
Novelty:  0.01971429
p_int:  0.841453632
p_ni:  0.158546368
Score:  0.183
Data Source:  BioPlex,STRINGDB
ZSCAN4
Tbio
Family:  TF
Novelty:  0.03803132
Score:  0.569
Data Source:  STRINGDB
WDR93
Tdark
Novelty:  4.56619985
Score:  0.555
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
5
7
96.5
1
1
1
31.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
7
96.5
1
31.4
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 92
701913
Mouse
MGI:3034723
544806
Dog
transmembrane protein 92
VGNC:47615
609270
Horse
transmembrane protein 92
VGNC:24325
100056325
Cow
transmembrane protein 92
VGNC:36127
507710
Species
Name
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 92
Mouse
Dog
transmembrane protein 92
Horse
transmembrane protein 92
Cow
transmembrane protein 92
Publication Statistics
PubMed Score 1.45
PubMed score by year
PubTator Score 2.42
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title