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Tdark
TMEM63B
CSC1-like protein 2

Protein Summary
Description
Acts as an osmosensitive calcium-permeable cation channel.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000259746
  • ENSP00000259746
  • ENSG00000137216
  • ENST00000323267
  • ENSP00000327154

Symbol
  • C6orf110
  • C6orf110
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor
0.71
transcription factor perturbation
0.61
histone modification site profile
0.6
cell type or tissue
0.58
transcription factor binding site profile
0.54


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.76   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 34   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.76   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 34   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0