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Tdark
TMEM39B
Transmembrane protein 39B

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.29   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 25   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.29   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 25   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (39)
OPALIN
Tdark
Novelty:  0.08221612
p_int:  0.99967017
p_ni:  0.000329734
p_wrong:  9.6e-8
Data Source:  BioPlex
NRG1
Tbio
Novelty:  0.00095246
p_int:  0.99781676
p_ni:  0.002183197
p_wrong:  4.2e-8
Score:  0.19
Data Source:  BioPlex,STRINGDB
SEMA7A
Tbio
Novelty:  0.00741605
p_int:  0.99432854
p_ni:  0.005671456
p_wrong:  4e-9
Score:  0.165
Data Source:  BioPlex,STRINGDB
SCN3B
Tbio
Family:  IC
Novelty:  0.0438123
p_int:  0.994153251
p_ni:  0.005846745
p_wrong:  4e-9
Data Source:  BioPlex
ADAM33
Tchem
Family:  Enzyme
Novelty:  0.00584097
p_int:  0.993657288
p_ni:  0.005911166
p_wrong:  0.000431546
Data Source:  BioPlex
PBXIP1
Tbio
Novelty:  0.15404864
p_int:  0.980892962
p_ni:  0.019103077
p_wrong:  0.00000396
Data Source:  BioPlex
ARSE
Tbio
Family:  Enzyme
Novelty:  0.00151862
p_int:  0.980021975
p_ni:  0.016532151
p_wrong:  0.003445875
Data Source:  BioPlex
B4GAT1
Tbio
Family:  Enzyme
Novelty:  0.14959923
p_int:  0.959745707
p_ni:  0.040246007
p_wrong:  0.000008287
Score:  0.154
Data Source:  BioPlex,STRINGDB
KLRD1
Tbio
Novelty:  0.00218019
p_int:  0.946622895
p_ni:  0.053131564
p_wrong:  0.000245541
Data Source:  BioPlex
CSTL1
Tbio
Novelty:  0.13370814
p_int:  0.941755964
p_ni:  0.057730617
p_wrong:  0.000513418
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sleep duration
1
1
0
3.8
17.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sleep duration
0
3.8
17.8
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 39B
VGNC:1682
456708
Macaque
transmembrane protein 39B
706700
Mouse
MGI:2682939
230770
Rat
RGD:1359450
362608
Dog
transmembrane protein 39B
VGNC:47577
487315
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 39B
Macaque
transmembrane protein 39B
Mouse
Rat
Dog
transmembrane protein 39B
Publication Statistics
PubMed Score 0.29
PubMed score by year
PubTator Score 0.07
PubTator score by year
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Related Publications
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PMID
Year
Title