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Tdark
TMEM255B
Transmembrane protein 255B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000375353
  • ENSP00000364502
  • ENSG00000184497

Symbol
  • FAM70B
  • FAM70B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.74
cell type or tissue
0.65
tissue sample
0.56
cell line
0.43
cellular component
0.38


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.58   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 34   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.58   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 34   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (18)
PHYHIP
Tdark
Family:  Enzyme
Novelty:  0.25773185
p_int:  0.987254947
p_ni:  0.012653197
p_wrong:  0.000091856
Score:  0.269
Data Source:  BioPlex,STRINGDB
WWP1
Tbio
Family:  Enzyme
Novelty:  0.01407874
p_int:  0.945034663
p_ni:  0.054965337
Score:  0.345
Data Source:  BioPlex,STRINGDB
DGAT2L6
Tbio
Family:  Enzyme
Novelty:  1.93122199
Score:  0.75
Data Source:  STRINGDB
UBALD2
Tdark
Novelty:  2.21418301
Score:  0.602
Data Source:  STRINGDB
RNF220
Tbio
Family:  Enzyme
Novelty:  0.14024436
Score:  0.539
Data Source:  STRINGDB
ABI3BP
Tbio
Novelty:  0.0916076
Score:  0.536
Data Source:  STRINGDB
MXRA8
Tdark
Novelty:  0.00509012
Score:  0.532
Data Source:  STRINGDB
LRRC37B
Tdark
Novelty:  0.60307987
Score:  0.529
Data Source:  STRINGDB
TMEM178A
Tdark
Novelty:  0.78925677
Score:  0.52
Data Source:  STRINGDB
DCUN1D2
Tchem
Novelty:  1.02957984
Score:  0.51
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (16)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
5
5
5
97.2
triglyceride measurement
4
4
5
95.6
HbA1c measurement
3
3
3
94.9
total cholesterol measurement
2
2
2
91
apolipoprotein B measurement
2
2
2
89.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
5
97.2
triglyceride measurement
5
95.6
HbA1c measurement
3
94.9
total cholesterol measurement
2
91
apolipoprotein B measurement
2
89.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2685533
272465
Dog
transmembrane protein 255B [Source:HGNC Symbol;Acc:HGNC:28297]
Cow
transmembrane protein 255B
VGNC:36065
618499
Pig
transmembrane protein 255B
100738464
Opossum
transmembrane protein 255B [Source:HGNC Symbol;Acc:HGNC:28297]
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Dog
transmembrane protein 255B [Source:HGNC Symbol;Acc:HGNC:28297]
Cow
transmembrane protein 255B
Pig
transmembrane protein 255B
Opossum
transmembrane protein 255B [Source:HGNC Symbol;Acc:HGNC:28297]
Publication Statistics
PubMed Score 1.58
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
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PMID
Year
Title