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Tdark
TMEM255A
Transmembrane protein 255A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000309720
  • ENSP00000310110
  • ENSG00000125355
  • ENST00000371352
  • ENSP00000360403
  • ENST00000371369
  • ENSP00000360420
  • ENST00000440464
  • ENSP00000405781

Symbol
  • FAM70A
  • FAM70A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.68
microRNA
0.65
transcription factor
0.52
tissue sample
0.49
kinase perturbation
0.48


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.96   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 81   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.96   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 81   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (37)
GCA
Tbio
Novelty:  0.01485875
p_int:  0.999949979
p_ni:  0.000049992
p_wrong:  2.9e-8
Score:  0.295
Data Source:  BioPlex,STRINGDB
KCTD2
Tdark
Novelty:  0.42992811
p_int:  0.998127649
p_ni:  0.001857378
p_wrong:  0.000014973
Score:  0.234
Data Source:  BioPlex,STRINGDB
ANKRD13D
Tdark
Novelty:  2.14380936
p_int:  0.996139467
p_ni:  0.003858207
p_wrong:  0.000002326
Score:  0.193
Data Source:  BioPlex,STRINGDB
ITCH
Tbio
Family:  Enzyme
Novelty:  0.00681861
p_int:  0.98374744
p_ni:  0.01625256
Score:  0.163
Data Source:  BioPlex,STRINGDB
WWP1
Tbio
Family:  Enzyme
Novelty:  0.01407874
p_int:  0.98306597
p_ni:  0.01693403
Score:  0.193
Data Source:  BioPlex,STRINGDB
WWP2
Tbio
Family:  Enzyme
Novelty:  0.01935799
p_int:  0.975778515
p_ni:  0.024221485
Score:  0.189
Data Source:  BioPlex,STRINGDB
NEDD4
Tchem
Family:  Enzyme
Novelty:  0.00281725
p_int:  0.965469642
p_ni:  0.034530358
Score:  0.173
Data Source:  BioPlex,STRINGDB
SEC24B
Tbio
Novelty:  0.01031644
p_int:  0.812933651
p_ni:  0.187066346
p_wrong:  3e-9
Score:  0.295
Data Source:  BioPlex,STRINGDB
XPNPEP2
Tchem
Family:  Enzyme
Novelty:  0.01453123
Score:  0.713
Data Source:  STRINGDB
LIX1
Tbio
Novelty:  0.03028158
Score:  0.608
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
leukocyte count
1
1
1
35
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
leukocyte count
1
35
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 255A
696050
Mouse
MGI:3045722
245386
Rat
RGD:727788
313453
Dog
transmembrane protein 255A
VGNC:47560
481035
Horse
transmembrane protein 255A
VGNC:24276
100055277
Species
Name
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 255A
Mouse
Rat
Dog
transmembrane protein 255A
Horse
transmembrane protein 255A
Publication Statistics
PubMed Score 0.96
PubMed score by year
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Related Publications
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0 of 0
PMID
Year
Title