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Tdark
TMEM247
Transmembrane protein 247

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000434431
  • ENSP00000388684
  • ENSG00000284701
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.59
cell line
0.58
cellular component
0.5
gene perturbation
0.4
cell type or tissue
0.31


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.13   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.13   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (9)
ZFAT
Tbio
Family:  TF
Novelty:  0.0283253
Score:  0.592
Data Source:  STRINGDB
R3HCC1
Tdark
Novelty:  1.93729169
Score:  0.516
Data Source:  STRINGDB
FAM149A
Tdark
Novelty:  0.58381103
Score:  0.515
Data Source:  STRINGDB
GRID2
Tbio
Family:  IC
Novelty:  0.00628904
Score:  0.494
Data Source:  STRINGDB
SVOPL
Tdark
Novelty:  0.46448049
Score:  0.461
Data Source:  STRINGDB
FAM155B
Tbio
Novelty:  0.0808512
Score:  0.428
Data Source:  STRINGDB
HMHB1
Tbio
Novelty:  0.47629958
Score:  0.426
Data Source:  STRINGDB
TAF8
Tbio
Novelty:  0.01056638
Score:  0.424
Data Source:  STRINGDB
TRIM8
Tbio
Family:  Enzyme
Novelty:  0.00545118
Score:  0.42
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
1
1
6.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
6.9
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 247
717746
Mouse
MGI:1925719
78469
Dog
transmembrane protein 247
VGNC:54551
611864
Horse
transmembrane protein 247
VGNC:51419
100630604
Cow
transmembrane protein 247
768009
Species
Name
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 247
Mouse
Dog
transmembrane protein 247
Horse
transmembrane protein 247
Cow
transmembrane protein 247
Publication Statistics
PubMed Score 0.13
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title