You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
TMEM205
Transmembrane protein 205

Protein Summary
Description
In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000354882
  • ENSP00000346954
  • ENSG00000105518
  • ENST00000447337
  • ENSP00000398258
  • ENST00000586590
  • ENSP00000466986
  • ENST00000586956
  • ENSP00000465483
  • ENST00000587948
  • ENSP00000465149
  • ENST00000588560
  • ENSP00000466495
  • ENST00000589555
  • ENSP00000465553
  • ENST00000593256
  • ENSP00000468733

Symbol
  • UNQ501
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.85
histone modification site profile
0.77
gene perturbation
0.74
small molecule perturbation
0.68
disease perturbation
0.62


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.55   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 107   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.55   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 107   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0