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Tdark
TMEM19
Transmembrane protein 19

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000266673
  • ENSP00000266673
  • ENSG00000139291
  • ENST00000549735
  • ENSP00000449955
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
1
transcription factor perturbation
0.94
histone modification site profile
0.73
cell line
0.65
microRNA
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.77   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 32   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.77   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 32   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (26)
TMEM154
Tdark
Novelty:  0.08935925
p_int:  0.978460568
p_ni:  1.7e-8
p_wrong:  0.021539415
Data Source:  BioPlex
MFSD13A
Tdark
Novelty:  0.39321369
Score:  0.679
Data Source:  STRINGDB
INO80D
Tdark
Novelty:  0.33070971
Score:  0.619
Data Source:  STRINGDB
THAP2
Tbio
Family:  TF
Novelty:  0.21339518
Score:  0.605
Data Source:  STRINGDB
NTN5
Tdark
Novelty:  0.59518421
Score:  0.561
Data Source:  STRINGDB
TMEM216
Tbio
Novelty:  0.07870718
Score:  0.553
Data Source:  STRINGDB
PQLC3
Tdark
Novelty:  2.0324719
Score:  0.548
Data Source:  STRINGDB
BSCL2
Tbio
Novelty:  0.00483959
Score:  0.547
Data Source:  STRINGDB
FAM49A
Tdark
Novelty:  0.40489408
Score:  0.536
Data Source:  STRINGDB
TTC39C
Tdark
Novelty:  0.44729145
Score:  0.533
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
4
1
4
75.3
1
1
0
1.2
74.2
Cleft palate
1
1
0
1.2
74.2
apolipoprotein B measurement
2
1
2
58.5
body mass index
2
1
2
47.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
4
75.3
0
1.2
74.2
Cleft palate
0
1.2
74.2
apolipoprotein B measurement
2
58.5
body mass index
2
47.7
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 19
VGNC:13473
452078
Mouse
MGI:1914476
67226
Rat
RGD:735209
299800
Dog
transmembrane protein 19
VGNC:47514
474450
Horse
transmembrane protein 19
VGNC:24238
100064665
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 19
Mouse
Rat
Dog
transmembrane protein 19
Horse
transmembrane protein 19
Publication Statistics
PubMed Score 0.77
PubMed score by year
PubTator Score 0.07
PubTator score by year
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Related Publications
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PMID
Year
Title