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Tbio
TMEM184A
Transmembrane protein 184A

Protein Summary
Description
Acts as a heparin receptor in vascular cells (By similarity). May be involved in vesicle transport in exocrine cells and Sertoli cells (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000297477
  • ENSP00000297477
  • ENSG00000164855

Symbol
  • SDMG1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.88
gene perturbation
0.74
transcription factor
0.58
cellular component
0.5
transcription factor binding site profile
0.49


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.02   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 76   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.02   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (50)
ALDH4A1
Tbio
Family:  Enzyme
Novelty:  0.01316227
p_int:  0.999998993
p_ni:  9.97e-7
p_wrong:  1.1e-8
Score:  0.232
Data Source:  BioPlex,STRINGDB
PDP2
Tbio
Family:  Enzyme
Novelty:  0.0259516
p_int:  0.999997382
p_ni:  0.000002616
p_wrong:  2e-9
Score:  0.192
Data Source:  BioPlex,STRINGDB
HIBCH
Tbio
Family:  Enzyme
Novelty:  0.02964018
p_int:  0.999990364
p_ni:  0.000009636
Score:  0.181
Data Source:  BioPlex,STRINGDB
GTF2F2
Tbio
Novelty:  0.02446629
p_int:  0.999923478
p_ni:  0.000073511
p_wrong:  0.000003011
Score:  0.188
Data Source:  BioPlex,STRINGDB
ME2
Tbio
Novelty:  0.03635548
p_int:  0.999710788
p_ni:  0.000289212
Score:  0.313
Data Source:  BioPlex,STRINGDB
YARS2
Tbio
Family:  Enzyme
Novelty:  0.00522139
p_int:  0.999456307
p_ni:  0.000543693
Data Source:  BioPlex
IBA57
Tbio
Family:  Enzyme
Novelty:  0.06327415
p_int:  0.99925925
p_ni:  0.00074075
Data Source:  BioPlex
KCTD15
Tbio
Novelty:  0.05277304
p_int:  0.998965741
p_ni:  0.000714181
p_wrong:  0.000320077
Score:  0.181
Data Source:  BioPlex,STRINGDB
RBM38
Tbio
Novelty:  0.03491566
p_int:  0.99882614
p_ni:  0.001166145
p_wrong:  0.000007715
Score:  0.165
Data Source:  BioPlex,STRINGDB
ASS1
Tbio
Family:  Enzyme
Novelty:  0.00358761
p_int:  0.997725303
p_ni:  0.002274697
Score:  0.165
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (9)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking initiation
1
1
1
6.5
smoking behavior
1
1
1
6.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking initiation
1
6.5
smoking behavior
1
6.3
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 184A
697461
Mouse
MGI:2385897
231832
Rat
RGD:1306702
304325
Dog
transmembrane protein 184A
VGNC:47508
100856376
Horse
transmembrane protein 184A
VGNC:24232
100053430
Species
Name
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 184A
Mouse
Rat
Dog
transmembrane protein 184A
Horse
transmembrane protein 184A
Publication Statistics
PubMed Score 8.02
PubMed score by year
PubTator Score 1.50
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title