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Tdark
TMEM169
Transmembrane protein 169

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295658
  • ENSP00000295658
  • ENSG00000163449
  • ENST00000406027
  • ENSP00000384100
  • ENST00000437356
  • ENSP00000401305
  • ENST00000454545
  • ENSP00000412524
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.81
virus perturbation
0.59
cell line
0.58
microRNA
0.53
cell type or tissue
0.51


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.13   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 23   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.13   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 23   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (31)
INKA2
Tdark
Novelty:  0.57898295
Score:  0.733
Data Source:  STRINGDB
NKAIN1
Tdark
Family:  Enzyme
Novelty:  0.52190272
Score:  0.72
Data Source:  STRINGDB
SLC10A4
Tbio
Family:  Transporter
Novelty:  0.1560734
Score:  0.711
Data Source:  STRINGDB
NDUFAF8
Tbio
Novelty:  1.48457646
Score:  0.527
Data Source:  STRINGDB
CLSTN2
Tbio
Novelty:  0.011364
Score:  0.527
Data Source:  STRINGDB
LPAR2
Tchem
Family:  GPCR
Novelty:  0.00794134
Score:  0.494
Data Source:  STRINGDB
TNS1
Tbio
Novelty:  0.00163046
Score:  0.469
Data Source:  STRINGDB
TMEM241
Tdark
Novelty:  1.02586788
Score:  0.455
Data Source:  STRINGDB
CCDC81
Tdark
Novelty:  2.58836864
Score:  0.452
Data Source:  STRINGDB
TEPSIN
Tdark
Novelty:  0.48775142
Score:  0.45
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
1
49.5
1
1
0
1.4
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
49.5
0
1.4
24.5
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 169
VGNC:2886
470640
Mouse
MGI:2442781
271711
Rat
RGD:1582820
690294
Dog
transmembrane protein 169
610243
Horse
transmembrane protein 169
VGNC:24218
100054987
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 169
Mouse
Rat
Dog
transmembrane protein 169
Horse
transmembrane protein 169
Publication Statistics
PubMed Score 0.13
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title