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Tbio
TMEM161B
Transmembrane protein 161B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000296595
  • ENSP00000296595
  • ENSG00000164180
  • ENST00000510089
  • ENSP00000423380

Symbol
  • FLB3342
  • PRO1313
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.9
kinase perturbation
0.76
cell type or tissue
0.7
transcription factor binding site profile
0.7
tissue sample
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.22   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 71   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.22   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 71   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (19)
CCR6
Tchem
Family:  GPCR
Novelty:  0.00257933
p_int:  0.999709147
p_ni:  0.000280861
p_wrong:  0.000009991
Data Source:  BioPlex
APLNR
Tchem
Family:  GPCR
Novelty:  0.00224203
p_int:  0.998468655
p_ni:  0.001531338
p_wrong:  8e-9
Data Source:  BioPlex
P2RY12
Tclin
Family:  GPCR
Novelty:  0.00035406
p_int:  0.997866722
p_ni:  0.002133275
p_wrong:  4e-9
Score:  0.207
Data Source:  BioPlex,STRINGDB
LPAR1
Tchem
Family:  GPCR
Novelty:  0.00318056
p_int:  0.996460655
p_ni:  0.003539344
p_wrong:  1e-9
Data Source:  BioPlex
YIPF3
Tbio
Novelty:  0.12021667
p_int:  0.983927005
p_ni:  0.016072994
p_wrong:  1e-9
Data Source:  BioPlex
FPR2
Tchem
Family:  GPCR
Novelty:  0.00228744
p_int:  0.983927005
p_ni:  0.016072994
p_wrong:  1e-9
Data Source:  BioPlex
IPPK
Tbio
Family:  Enzyme
Novelty:  0.02169701
p_int:  0.977662336
p_ni:  0.022265663
p_wrong:  0.000072002
Data Source:  BioPlex
TMCO5A
Tdark
Novelty:  0.77942349
Score:  0.653
Data Source:  STRINGDB
RFK
Tbio
Family:  Enzyme
Novelty:  0.00973729
Score:  0.545
Data Source:  STRINGDB
MEF2C
Tbio
Family:  TF
Novelty:  0.00232724
Score:  0.514
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
1
1
1
88.9
retinal vasculature measurement
1
1
1
66.8
educational attainment
1
4
4
62.9
neuroticism measurement
2
3
0
5.8
54.1
self reported educational attainment
1
1
1
53.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
88.9
retinal vasculature measurement
1
66.8
educational attainment
4
62.9
neuroticism measurement
0
5.8
54.1
self reported educational attainment
1
53.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 161B
VGNC:4200
471485
Macaque
transmembrane protein 161B
694351
Mouse
MGI:1919995
72745
Rat
RGD:1309660
309953
Dog
transmembrane protein 161B
VGNC:47490
488916
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 161B
Macaque
transmembrane protein 161B
Mouse
Rat
Dog
transmembrane protein 161B
Publication Statistics
PubMed Score 6.22
PubMed score by year
PubTator Score 1.48
PubTator score by year
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Related Publications
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PMID
Year
Title