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Tbio
TMEM132D
Transmembrane protein 132D

Protein Summary
Description
May serve as a cell-surface marker for oligodendrocyte differentiation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000389441
  • ENSP00000374092
  • ENSG00000151952
  • ENST00000422113
  • ENSP00000408581

Symbol
  • HBE120
  • KIAA1944
  • MOLT
  • MOLT
  • PPP1R153
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.97
gene perturbation
0.83
phenotype
0.77
microRNA
0.59
cell type or tissue
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.88   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 84   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.88   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 84   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (26)
SETMAR
Tbio
Family:  Epigenetic
Novelty:  0.02859547
Score:  0.805
Data Source:  STRINGDB
FABP5
Tchem
Novelty:  0.00570755
Score:  0.8
Data Source:  STRINGDB
PRPF19
Tbio
Novelty:  0.01616737
Score:  0.8
Data Source:  STRINGDB
GLT1D1
Tdark
Family:  Enzyme
Novelty:  0.33685691
Score:  0.645
Data Source:  STRINGDB
GOT2
Tbio
Family:  Enzyme
Novelty:  0.00054023
Score:  0.548
Data Source:  STRINGDB
SLC15A4
Tbio
Family:  Transporter
Novelty:  0.01325014
Score:  0.514
Data Source:  STRINGDB
MEGF11
Tdark
Novelty:  0.25713867
Score:  0.51
Data Source:  STRINGDB
C1D
Tbio
Novelty:  0.00997109
Score:  0.504
Data Source:  STRINGDB
ANXA5
Tbio
Novelty:  0.00007584
Score:  0.503
Data Source:  STRINGDB
FABP3
Tchem
Novelty:  0.00142249
Score:  0.501
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sleep measurement
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sleep measurement
1
21.5
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 132D
VGNC:8579
467159
Mouse
MGI:3044963
243274
Rat
RGD:735062
288750
Dog
transmembrane protein 132D
VGNC:47470
486233
Horse
transmembrane protein 132D
VGNC:24195
100147694
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 132D
Mouse
Rat
Dog
transmembrane protein 132D
Horse
transmembrane protein 132D
Publication Statistics
PubMed Score 15.88
PubMed score by year
PubTator Score 13.71
PubTator score by year
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Related Publications
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PMID
Year
Title