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Tdark
TMEM128
Transmembrane protein 128

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.16   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 9   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.16   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 9   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (41)
RTN4
Tbio
Novelty:  0.00080371
p_int:  0.999997691
p_ni:  0.000002309
Score:  0.641
Data Source:  BioPlex,STRINGDB
REEP6
Tbio
Novelty:  0.10645981
p_int:  0.999952679
p_ni:  0.000047321
Score:  0.195
Data Source:  BioPlex,STRINGDB
SLC44A1
Tbio
Family:  Transporter
Novelty:  0.01499456
p_int:  0.99995118
p_ni:  0.000036385
p_wrong:  0.000012435
Score:  0.165
Data Source:  BioPlex,STRINGDB
CD226
Tbio
Novelty:  0.00374102
p_int:  0.999651191
p_ni:  2.22e-7
p_wrong:  0.000348587
Data Source:  BioPlex
RTN2
Tbio
Novelty:  0.05184418
p_int:  0.9996495
p_ni:  0.000350493
p_wrong:  7e-9
Score:  0.195
Data Source:  BioPlex,STRINGDB
REEP5
Tbio
Novelty:  0.00160455
p_int:  0.998974482
p_ni:  0.001025462
p_wrong:  5.6e-8
Score:  0.356
Data Source:  BioPlex,STRINGDB
FUNDC2
Tbio
Novelty:  0.09695817
p_int:  0.997680417
p_ni:  0.00174486
p_wrong:  0.000574723
Score:  0.165
Data Source:  BioPlex,STRINGDB
PLSCR1
Tbio
Family:  Enzyme
Novelty:  0.01483138
p_int:  0.997070701
p_ni:  0.002814752
p_wrong:  0.000114547
Score:  0.542
Data Source:  BioPlex,STRINGDB
BCS1L
Tbio
Family:  Enzyme
Novelty:  0.01764582
p_int:  0.99414319
p_ni:  0.005856786
p_wrong:  2.3e-8
Data Source:  BioPlex
TMEM208
Tdark
Novelty:  0.63059333
p_int:  0.993029646
p_ni:  0.000130039
p_wrong:  0.006840315
Score:  0.719
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum metabolite measurement
1
1
1
6.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum metabolite measurement
1
6.5
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 128
VGNC:726
461088
Macaque
transmembrane protein 128 [Source:HGNC Symbol;Acc:HGNC:28201]
Mouse
MGI:1913559
66309
Rat
RGD:1310481
360952
Dog
transmembrane protein 128
VGNC:47462
479094
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 128
Macaque
transmembrane protein 128 [Source:HGNC Symbol;Acc:HGNC:28201]
Mouse
Rat
Dog
transmembrane protein 128
Publication Statistics
PubMed Score 0.16
PubMed score by year
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Related Publications
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0 of 0
PMID
Year
Title