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Tdark
TMEM120A
Transmembrane protein 120A

Protein Summary
Description
Necessary for efficient adipogenesis (PubMed:26024229).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000493111
  • ENSP00000473983
  • ENSG00000189077

Symbol
  • TMPIT
  • NET29
  • TMPIT
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.84
kinase perturbation
0.76
tissue sample
0.69
cell line
0.63
gene perturbation
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.82   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.82   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (51)
POMK
Tbio
Family:  Kinase
Novelty:  0.09340344
p_int:  0.999893652
p_ni:  0.000095692
p_wrong:  0.000010655
Score:  0.509
Data Source:  BioPlex,STRINGDB
ATP5PF
Tbio
Family:  Enzyme
Novelty:  0.00585408
p_int:  0.999753277
p_ni:  0.000242391
p_wrong:  0.000004332
Data Source:  BioPlex
TNFSF18
Tbio
Novelty:  0.01423949
p_int:  0.999666459
p_ni:  0.000054033
p_wrong:  0.000279508
Data Source:  BioPlex
JTB
Tbio
Novelty:  0.06646216
p_int:  0.998054038
p_ni:  0.001710722
p_wrong:  0.00023524
Data Source:  BioPlex
SYPL2
Tdark
Novelty:  0.03928948
p_int:  0.996844981
p_ni:  0.00315336
p_wrong:  0.000001659
Score:  0.189
Data Source:  BioPlex,STRINGDB
CD1A
Tbio
Novelty:  0.00090676
p_int:  0.996736025
p_ni:  0.001141131
p_wrong:  0.002122845
Data Source:  BioPlex
CLEC2D
Tbio
Novelty:  0.02501194
p_int:  0.996144026
p_ni:  0.003854811
p_wrong:  0.000001164
Data Source:  BioPlex
LRRC55
Tbio
Family:  IC
Novelty:  0.25121277
p_int:  0.996067539
p_ni:  0.003723811
p_wrong:  0.000208649
Data Source:  BioPlex
CTLA4
Tclin
Novelty:  0.00012781
p_int:  0.995206086
p_ni:  0.004474445
p_wrong:  0.000319469
Data Source:  BioPlex
YIPF3
Tbio
Novelty:  0.12021667
p_int:  0.990577915
p_ni:  0.006490667
p_wrong:  0.002931418
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (25)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
coffee consumption measurement
4
4
5
97.2
mean platelet volume
2
2
2
90.9
tea consumption measurement
2
1
2
84.9
testosterone measurement
5
1
5
84
glomerular filtration rate
3
2
3
83
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
coffee consumption measurement
5
97.2
mean platelet volume
2
90.9
tea consumption measurement
2
84.9
testosterone measurement
5
84
glomerular filtration rate
3
83
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2686991
215210
Rat
RGD:1311474
288591
Cow
transmembrane protein 120A
VGNC:35956
520173
Chicken
transmembrane protein 120A
CGNC:1399
417519
Xenopus
transmembrane protein 120A
XB-GENE-5858565
548366
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Cow
transmembrane protein 120A
Chicken
transmembrane protein 120A
Xenopus
transmembrane protein 120A
Publication Statistics
PubMed Score 8.82
PubMed score by year
PubTator Score 0.25
PubTator score by year
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Related Publications
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PMID
Year
Title