You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
TMEM106A
Transmembrane protein 106A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000541594
  • ENSP00000439844
  • ENSG00000184988
  • ENST00000588659
  • ENSP00000466820
  • ENST00000612339
  • ENSP00000483246
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.83
tissue sample
0.7
co-expressed gene
0.69
transcription factor binding site profile
0.68
virus perturbation
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.06   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 53   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.06   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 53   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (54)
LRRC3
Tdark
Novelty:  0.13484671
p_int:  0.998825453
p_ni:  0.001134959
p_wrong:  0.000039589
Data Source:  BioPlex
GAS6
Tbio
Novelty:  0.00297606
p_int:  0.998449236
p_ni:  0.001550762
p_wrong:  3e-9
Data Source:  BioPlex
NMU
Tbio
Novelty:  0.00326109
p_int:  0.997791243
p_ni:  0.002147408
p_wrong:  0.00006135
Data Source:  BioPlex
GALNT12
Tbio
Family:  Enzyme
Novelty:  0.085131
p_int:  0.995179969
p_ni:  0.004820031
Data Source:  BioPlex
SUN1
Tbio
Novelty:  0.00931817
p_int:  0.993854715
p_ni:  0.006145285
Data Source:  BioPlex
NSUN3
Tbio
Family:  Enzyme
Novelty:  0.15268529
p_int:  0.991077976
p_ni:  0.008921715
p_wrong:  3.09e-7
Data Source:  BioPlex
DAG1
Tbio
Family:  Enzyme
Novelty:  0.00149278
p_int:  0.990205169
p_ni:  0.009794792
p_wrong:  3.9e-8
Data Source:  BioPlex
FAM3C
Tbio
Novelty:  0.04598347
p_int:  0.985819514
p_ni:  0.00669962
p_wrong:  0.007480866
Data Source:  BioPlex
GCNT1
Tbio
Family:  Enzyme
Novelty:  0.01487872
p_int:  0.975320199
p_ni:  0.024505696
p_wrong:  0.000174105
Data Source:  BioPlex
PRXL2A
Tchem
Novelty:  0.01336664
p_int:  0.974127583
p_ni:  0.025871307
p_wrong:  0.000001111
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
1
1
1
13.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
1
13.3
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 106A
712913
Mouse
MGI:1922056
217203
Rat
RGD:1309043
287722
Dog
transmembrane protein 106A
VGNC:47446
490951
Horse
transmembrane protein 106A
VGNC:24176
100065621
Species
Name
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 106A
Mouse
Rat
Dog
transmembrane protein 106A
Horse
transmembrane protein 106A
Publication Statistics
PubMed Score 5.06
PubMed score by year
PubTator Score 2.38
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title