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Tbio
TMEM102
Transmembrane protein 102

Protein Summary
Description
Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000323206
  • ENSP00000315387
  • ENSG00000181284
  • ENST00000396568
  • ENSP00000379815
  • ENST00000638427
  • ENSP00000491063
  • ENSG00000284228
  • ENST00000639387
  • ENSP00000491290

Symbol
  • CBAP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.76
transcription factor
0.67
cell type or tissue
0.64
biological process
0.61
tissue sample
0.57


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.56   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 80   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.56   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (23)
RAB3IL1
Tbio
Novelty:  0.0167537
p_int:  0.999999995
p_ni:  3e-9
p_wrong:  2e-9
Score:  0.693
Data Source:  BioPlex,STRINGDB
GDF5
Tbio
Novelty:  0.00218118
p_int:  0.999999991
p_ni:  5e-9
p_wrong:  4e-9
Score:  0.553
Data Source:  BioPlex,STRINGDB
PCMT1
Tbio
Family:  Enzyme
Novelty:  0.01414946
p_int:  0.999997541
p_ni:  0.000002459
Score:  0.202
Data Source:  BioPlex,STRINGDB
TRAF2
Tbio
Novelty:  0.00983658
p_int:  0.999977684
p_ni:  0.000021638
p_wrong:  6.79e-7
Score:  0.193
Data Source:  BioPlex,STRINGDB
ZC3H3
Tbio
Novelty:  0.26894046
p_int:  0.983878956
p_ni:  0.00011755
p_wrong:  0.016003494
Score:  0.191
Data Source:  BioPlex,STRINGDB
GIMAP8
Tbio
Family:  Enzyme
Novelty:  0.13237721
Score:  0.72
Data Source:  STRINGDB
ZNF613
Tdark
Family:  TF
Novelty:  1.06161745
Score:  0.717
Data Source:  STRINGDB
FDXR
Tbio
Family:  Enzyme
Novelty:  0.00171588
Score:  0.702
Data Source:  STRINGDB
GIMAP7
Tbio
Family:  Enzyme
Novelty:  0.15758026
Score:  0.625
Data Source:  STRINGDB
GNG10
Tdark
Novelty:  0.37659459
Score:  0.598
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (14)
Find Similar Targets
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
MGI
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
GOC
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (60)
Items per page:
1 – 5 of 60
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
2
11
12
99.5
testosterone measurement
2
11
12
99.5
serum non-albumin protein measurement
1
3
3
92
serum non-albumin protein measurement
1
3
3
92
body height
2
2
2
84.1
Items per page:
1 – 5 of 60
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
12
99.5
testosterone measurement
12
99.5
serum non-albumin protein measurement
3
92
serum non-albumin protein measurement
3
92
body height
2
84.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1921591
380705
Rat
RGD:1559450
497937
Dog
transmembrane protein 102
VGNC:49837
111089959
Horse
transmembrane protein 102
VGNC:52445
100061842
Cow
transmembrane protein 102
VGNC:35943
508014
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
transmembrane protein 102
Horse
transmembrane protein 102
Cow
transmembrane protein 102
Publication Statistics
PubMed Score 6.56
PubMed score by year
PubTator Score 3.23
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title