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Tbio
TMED3
Transmembrane emp24 domain-containing protein 3

Protein Summary
Description
Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000299705
  • ENSP00000299705
  • ENSG00000166557
  • ENST00000424155
  • ENSP00000414983

Symbol
  • C15orf22
  • p26
  • P24B
  • p24g4
  • C15orf22
  • p24gamma4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.95
histone modification site profile
0.71
cellular component
0.66
kinase perturbation
0.66
tissue sample
0.59


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28.87   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 141   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28.87   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 141   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0