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Tdark
TLDC2
TLD domain-containing protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000217320
  • ENSP00000217320
  • ENSG00000101342
  • ENST00000602922
  • ENSP00000473323

Symbol
  • C20orf118
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.93
cell line
0.57
tissue
0.57
tissue sample
0.57
microRNA
0.48


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.24   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 36   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.24   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 36   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (23)
ATP6V1C1
Tbio
Family:  Enzyme
Novelty:  0.03660846
p_int:  0.999886447
p_ni:  0.000113553
Score:  0.227
Data Source:  BioPlex,STRINGDB
ATP6V1D
Tbio
Family:  Enzyme
Novelty:  0.02298626
p_int:  0.996534028
p_ni:  0.00346484
p_wrong:  0.000001131
Score:  0.201
Data Source:  BioPlex,STRINGDB
ATP6V1E1
Tbio
Family:  Enzyme
Novelty:  0.04832113
p_int:  0.991124364
p_ni:  0.008875636
Score:  0.385
Data Source:  BioPlex,STRINGDB
ATP6V1B2
Tchem
Family:  Enzyme
Novelty:  0.01767911
p_int:  0.963947773
p_ni:  0.036052227
Score:  0.282
Data Source:  BioPlex,STRINGDB
KLHL15
Tbio
Novelty:  0.54712519
p_int:  0.842424544
p_ni:  0.157575456
Score:  0.192
Data Source:  BioPlex,STRINGDB
AAK1
Tchem
Family:  Kinase
Novelty:  0.02438961
Score:  0.617
Data Source:  STRINGDB
OR4C13
Tdark
Family:  oGPCR
Novelty:  2.38132296
Score:  0.559
Data Source:  STRINGDB
OR6N2
Tdark
Family:  oGPCR
Novelty:  0.67142074
Score:  0.554
Data Source:  STRINGDB
OR51H1
Tdark
Family:  oGPCR
Novelty:  17
Score:  0.543
Data Source:  STRINGDB
FREM3
Tdark
Novelty:  0.16573809
Score:  0.541
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
suntan
1
2
2
94.6
red blood cell distribution width
1
1
1
13.2
lymphocyte percentage of leukocytes
1
1
1
8.2
lymphocyte count
1
1
1
6.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
suntan
2
94.6
red blood cell distribution width
1
13.2
lymphocyte percentage of leukocytes
1
8.2
lymphocyte count
1
6.5
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
TBC/LysM-associated domain containing 2
709257
Mouse
MGI:2686178
383766
Rat
RGD:1561343
502689
Dog
TBC/LysM-associated domain containing 2
VGNC:47395
485861
Horse
TBC/LysM-associated domain containing 2
VGNC:24128
100069754
Species
Name
OMA
EggNOG
Inparanoid
Macaque
TBC/LysM-associated domain containing 2
Mouse
Rat
Dog
TBC/LysM-associated domain containing 2
Horse
TBC/LysM-associated domain containing 2
Publication Statistics
PubMed Score 1.24
PubMed score by year
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Related Publications
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PMID
Year
Title