You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
TIGD7
Tigger transposable element-derived protein 7

Protein Summary
Description
The protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000396862
  • ENSP00000380071
  • ENSG00000140993

Symbol
  • Sancho
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.78
tissue sample
0.6
protein domain
0.58
cell line
0.54
tissue
0.52


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.28   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 44   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.28   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 44   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (33)
UACA
Tbio
Novelty:  0.05853699
p_int:  0.999585143
p_ni:  0.000414776
p_wrong:  8.1e-8
Score:  0.537
Data Source:  BioPlex,STRINGDB
FBP1
Tchem
Family:  Enzyme
Novelty:  0.0029987
p_int:  0.977344327
p_ni:  0.022588385
p_wrong:  0.000067288
Score:  0.359
Data Source:  BioPlex,STRINGDB
PRMT8
Tchem
Family:  Epigenetic
Novelty:  0.04213384
p_int:  0.760942595
p_ni:  0.239057392
p_wrong:  1.3e-8
Score:  0.194
Data Source:  BioPlex,STRINGDB
ZNF648
Tdark
Family:  TF
Novelty:  0.57586282
Score:  0.745
Data Source:  STRINGDB
STARD7
Tbio
Novelty:  0.04511594
Score:  0.702
Data Source:  STRINGDB
ZNF75A
Tdark
Family:  TF
Novelty:  1.05456752
Score:  0.672
Data Source:  STRINGDB
ZNF200
Tdark
Family:  TF
Novelty:  0.69520683
Score:  0.644
Data Source:  STRINGDB
KLK9
Tbio
Family:  Enzyme
Novelty:  0.0302278
Score:  0.642
Data Source:  STRINGDB
ZNF681
Tdark
Family:  TF
Novelty:  3.00740001
Score:  0.627
Data Source:  STRINGDB
ZNF213
Tbio
Family:  TF
Novelty:  0.24190639
Score:  0.575
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
4.8
73.7
heel bone mineral density
1
1
1
34.9
antisocial behaviour measurement
1
1
1
30.2
1
1
1
30.2
substance abuse
1
1
1
30.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
4.8
73.7
heel bone mineral density
1
34.9
antisocial behaviour measurement
1
30.2
1
30.2
substance abuse
1
30.2
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
tigger transposable element derived 7
VGNC:9116
101057026
Horse
tigger transposable element derived 7
VGNC:24106
102148332
Opossum
tigger transposable element derived 7 [Source:HGNC Symbol;Acc:HGNC:18331]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
tigger transposable element derived 7
Horse
tigger transposable element derived 7
Opossum
tigger transposable element derived 7 [Source:HGNC Symbol;Acc:HGNC:18331]
Publication Statistics
PubMed Score 7.28
PubMed score by year
PubTator Score 0.73
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title